Measles virus and cytomegalovirus co-infection, in a child with recent SARS-CoV-2 infection, during COVID-19 pandemic: a case report.


Journal

Virology journal
ISSN: 1743-422X
Titre abrégé: Virol J
Pays: England
ID NLM: 101231645

Informations de publication

Date de publication:
19 07 2023
Historique:
received: 17 02 2023
accepted: 13 06 2023
medline: 21 7 2023
pubmed: 20 7 2023
entrez: 19 7 2023
Statut: epublish

Résumé

Measles virus (MV) and cytomegalovirus (CMV) may cause pediatric infection. We report the first described case of MV and CMV co-infection in an unvaccinated 13-mo-old girl, with a recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, occurred during coronavirus disease 2019 (COVID-19) pandemic. The COVID-19 pandemic context, combined with patient's complex clinical scenario, presenting symptoms as persistent fever, diarrhea, vomiting, maculopapular rash and edema, in addition to high level of inflammatory markers, led to a suspicion of multisystemic inflammatory syndrome in children (MIS-C). The final diagnosis and the successfully management of the case, discharged after resolution of symptoms, was achieved by a proper virological diagnosis and a close two-way cooperation between pediatricians and clinical microbiologists. The report mainly highlights that awareness about measles should be raised in unvaccinated patients with consistent symptoms, even in the COVID-19 era.

Identifiants

pubmed: 37468989
doi: 10.1186/s12985-023-02099-8
pii: 10.1186/s12985-023-02099-8
pmc: PMC10354918
doi:

Types de publication

Case Reports Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

157

Informations de copyright

© 2023. The Author(s).

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Auteurs

Giulia Piccirilli (G)

Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy.

Monia Gennari (M)

Pediatric Emergency Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy.

Liliana Gabrielli (L)

Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy. liliana.gabrielli@aosp.bo.it.

Marta Leone (M)

Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, 40138, Italy.

Eva Caterina Borgatti (EC)

Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, 40138, Italy.

Alessia Cantiani (A)

Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, 40138, Italy.

Federica Lanna (F)

Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, 40138, Italy.

Fabio Magurano (F)

Department of Infectious Diseases, National Measles Reference Laboratory-WHO/LabNet, Istituto Superiore di Sanità (ISS), Rome, 00165, Italy.

Melissa Baggieri (M)

Department of Infectious Diseases, National Measles Reference Laboratory-WHO/LabNet, Istituto Superiore di Sanità (ISS), Rome, 00165, Italy.

Antonella Marangoni (A)

Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, 40138, Italy.

Marcello Lanari (M)

Pediatric Emergency Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy.
Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, 40138, Italy.

Tiziana Lazzarotto (T)

Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy.
Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, 40138, Italy.

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