Comparison of bleeding during trochanteric fracture fixation with mini-invasive or conventional side plate fixation: A randomized controlled trial.


Journal

Orthopaedics & traumatology, surgery & research : OTSR
ISSN: 1877-0568
Titre abrégé: Orthop Traumatol Surg Res
Pays: France
ID NLM: 101494830

Informations de publication

Date de publication:
11 2023
Historique:
received: 03 07 2022
revised: 04 03 2023
accepted: 06 06 2023
medline: 6 11 2023
pubmed: 21 7 2023
entrez: 20 7 2023
Statut: ppublish

Résumé

Trochanteric fractures are a public health issue due to the aging of the population. Treatment aims to reduce their related morbidity and mortality and to allow an early return to independence. Postoperative anemia is associated with poorer functional recovery and an increased mortality rate. The aim of this study was to assess whether minimally invasive side plate fixation (Minimal Invasive Screw System, MISS™) resulted in reduced perioperative bleeding compared with conventional fixation (Pertrochanteric Hip Screw, PHS™). We hypothesized that minimally invasive side plate fixation (MISS) would result in reduced perioperative bleeding compared with conventional fixation (PHS). We conducted an open randomized controlled trial with blinded assessment of the primary outcome. Inclusion criteria were patients aged over 65 years with isolated reducible trochanteric fracture. The 2 surgical implants were of the same shape, the only difference between them being the locking mode of the femoral neck screw on the plate of the MISS device, allowing a percutaneous approach. Primary outcome was perioperative bleeding evaluated with Mercuriali's formula. Secondary outcomes included operating time, scar length, length of hospital stay, radiological criteria such as quality of fracture reduction, implant positioning, bone healing, complications and functional recovery compared between the 2 groups. One hundred and eight patients met the inclusion criteria and were randomized to receive either PHS (n=54) or MISS (n=54). Osteosynthesis with MISS significatively reduced perioperative bleeding (median 243mL, interquartile range [152-410] vs. 334mL [247-430] [p=0.0299]), operating time (65min [57-73] vs. 79min [66-89] [p=0.0002]) and scar length after 45 days (7cm [5-8] vs. 14cm [12-15] [p<0.0001]). There was no statistically significant difference between groups in postoperative complications, revision surgery or serious adverse events. Compared with PHS, MISS reduced operating time, perioperative bleeding and scar length with no observed functional difference. I.

Sections du résumé

BACKGROUND
Trochanteric fractures are a public health issue due to the aging of the population. Treatment aims to reduce their related morbidity and mortality and to allow an early return to independence. Postoperative anemia is associated with poorer functional recovery and an increased mortality rate. The aim of this study was to assess whether minimally invasive side plate fixation (Minimal Invasive Screw System, MISS™) resulted in reduced perioperative bleeding compared with conventional fixation (Pertrochanteric Hip Screw, PHS™).
HYPOTHESIS
We hypothesized that minimally invasive side plate fixation (MISS) would result in reduced perioperative bleeding compared with conventional fixation (PHS).
PATIENTS AND METHODS
We conducted an open randomized controlled trial with blinded assessment of the primary outcome. Inclusion criteria were patients aged over 65 years with isolated reducible trochanteric fracture. The 2 surgical implants were of the same shape, the only difference between them being the locking mode of the femoral neck screw on the plate of the MISS device, allowing a percutaneous approach. Primary outcome was perioperative bleeding evaluated with Mercuriali's formula. Secondary outcomes included operating time, scar length, length of hospital stay, radiological criteria such as quality of fracture reduction, implant positioning, bone healing, complications and functional recovery compared between the 2 groups.
RESULTS
One hundred and eight patients met the inclusion criteria and were randomized to receive either PHS (n=54) or MISS (n=54). Osteosynthesis with MISS significatively reduced perioperative bleeding (median 243mL, interquartile range [152-410] vs. 334mL [247-430] [p=0.0299]), operating time (65min [57-73] vs. 79min [66-89] [p=0.0002]) and scar length after 45 days (7cm [5-8] vs. 14cm [12-15] [p<0.0001]). There was no statistically significant difference between groups in postoperative complications, revision surgery or serious adverse events.
CONCLUSION
Compared with PHS, MISS reduced operating time, perioperative bleeding and scar length with no observed functional difference.
LEVEL OF EVIDENCE
I.

Identifiants

pubmed: 37474020
pii: S1877-0568(23)00152-4
doi: 10.1016/j.otsr.2023.103661
pii:
doi:

Banques de données

ClinicalTrials.gov
['NCT01427036']

Types de publication

Randomized Controlled Trial Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

103661

Informations de copyright

Copyright © 2023 Elsevier Masson SAS. All rights reserved.

Auteurs

Marion Besnard (M)

Service de chirurgie orthopédique, centre hospitalier Robert-Debré, rue des Ursulines, 37403 Amboise cedex, France; Service de chirurgie orthopédique, hôpital Trousseau, centre hospitalier régional universitaire de Tours, 37044 Tours cedex 9, France. Electronic address: marion.besnard22@gmail.com.

Julie Léger (J)

Centre hospitalier régional universitaire de Tours, Inserm CIC1415, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.

Damien Babusiaux (D)

Service de chirurgie orthopédique, hôpital Trousseau, centre hospitalier régional universitaire de Tours, 37044 Tours cedex 9, France.

François Marty (F)

Service de chirurgie orthopédique, hôpital Trousseau, centre hospitalier régional universitaire de Tours, 37044 Tours cedex 9, France; Service d'orthopédie, centre hospitalier d'Albi, 22, boulevard du Général-Sibille, 81000 Albi, France.

Mickael Ropars (M)

Service de chirurgie orthopédique et traumatologique, centre hospitalier universitaire de Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France.

Philippe Rosset (P)

Service de chirurgie orthopédique, hôpital Trousseau, centre hospitalier régional universitaire de Tours, 37044 Tours cedex 9, France; Université François-Rabelais de Tours, PRES centre-Val de Loire université, 60, rue du Plat d'Étain, 37020 Tours cedex 1, France.

Louis-Romée Le Nail (LR)

Service de chirurgie orthopédique, hôpital Trousseau, centre hospitalier régional universitaire de Tours, 37044 Tours cedex 9, France; Université François-Rabelais de Tours, PRES centre-Val de Loire université, 60, rue du Plat d'Étain, 37020 Tours cedex 1, France; CNRS ERL 7001 Leukemic niche & redox metabolisme (LNOX)/Niche leucémique et métabolisme oxydatif, EA 7501 GICC, université de Tours, 60, rue du Plat d'Étain, 37020 Tours cedex 1, France.

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Classifications MeSH