Jejunal Feeding by Gastrojejunal Tube in Pediatric Refractory Gastroesophageal Reflux Disease.


Journal

Journal of pediatric gastroenterology and nutrition
ISSN: 1536-4801
Titre abrégé: J Pediatr Gastroenterol Nutr
Pays: United States
ID NLM: 8211545

Informations de publication

Date de publication:
01 08 2023
Historique:
medline: 24 7 2023
pubmed: 21 7 2023
entrez: 21 7 2023
Statut: ppublish

Résumé

The objective of this study is to determine whether jejunal nutrition by gastrojejunal tube (GJT) could be a therapeutic option for refractory gastroesophageal reflux disease (GERD), avoiding further antireflux surgery. A monocentric retrospective study was conducted for all children <18 years who underwent GJT placement to treat GERD. We collected data at the first GJT placement, 5 months after last GJT withdrawal, and at the end of the follow-up (June 2021). Among 46 GERD patients with 86 GJT, 32 (69.6%) and 30 (65.2%) avoided antireflux surgery 5 and 28 months, respectively, after the definitive GJT removal. Five months after GJT removal, discharge from hospital, transition to gastric nutrition, GERD complications, and treatment were significantly improved. Median age and weight at the first GJT placement were 7 months and 6.8 kg. Patients had digestive comorbidities or complicated GERD in 69.6% and 76.1% patients, respectively. The median duration of jejunal nutrition using GJT was 64.5 days. GJT had to be removed in 63 (75.9%) cases for technical problems. Jejunal nutrition by GJT could be an alternative to antireflux surgery avoiding sustainably antireflux surgery in most of complicated GERD patients. The high frequency of mechanical complications raises that these devices should be technically improved.

Identifiants

pubmed: 37477887
doi: 10.1097/MPG.0000000000003785
pii: 00005176-202308000-00025
doi:

Banques de données

ClinicalTrials.gov
['NCT05278689']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

267-273

Informations de copyright

Copyright © 2023 by European Society for European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

Déclaration de conflit d'intérêts

The authors report no conflicts of interest.

Références

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Auteurs

Nathan Faccioli (N)

From the Department of Pediatric Gastroenterology and Nutrition, Robert-Debré Universitary Hospital, APHP, Paris, France.

Anaïs Sierra (A)

From the Department of Pediatric Gastroenterology and Nutrition, Robert-Debré Universitary Hospital, APHP, Paris, France.
University of Paris-Cité, Paris, France.
the Department of Pediatrics, Hôpital Femme-Mère-Enfant, Hospices Civils de Lyon, Lyon, France.

Alexis Mosca (A)

From the Department of Pediatric Gastroenterology and Nutrition, Robert-Debré Universitary Hospital, APHP, Paris, France.

Marc Bellaïche (M)

From the Department of Pediatric Gastroenterology and Nutrition, Robert-Debré Universitary Hospital, APHP, Paris, France.

Hélène Lengliné (H)

From the Department of Pediatric Gastroenterology and Nutrition, Robert-Debré Universitary Hospital, APHP, Paris, France.

Arnaud Bonnard (A)

University of Paris-Cité, Paris, France.
the Department of Pediatric Surgery and Urology, Robert-Debré Universitary Hospital, APHP, Paris, France.
INSERM UMR 1149, Paris, France.

Jérôme Viala (J)

From the Department of Pediatric Gastroenterology and Nutrition, Robert-Debré Universitary Hospital, APHP, Paris, France.
University of Paris-Cité, Paris, France.
INSERM UMR 1149, Paris, France.

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