COVID-19 incidence and outcome by affluence/deprivation across three pandemic waves in Ireland: A retrospective cohort study using routinely collected data.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2023
Historique:
received: 04 07 2022
accepted: 11 06 2023
medline: 23 10 2023
pubmed: 21 7 2023
entrez: 21 7 2023
Statut: epublish

Résumé

Since the pandemic onset, deprivation has been seen as a significant determinant of COVID-19 incidence and mortality. This study explores outcomes of COVID-19 in the context of material deprivation across three pandemic waves in Ireland. Between 1st March 2020 and 13th May 2021, 252,637 PCR-confirmed COVID-19 cases were notified in Ireland. Cases were notified to the national Computerised Infectious Disease Reporting (CIDR) system. Each case was geo-referenced and assigned a deprivation category according to the Haase-Pratschke (HP) Deprivation Index. Regression modelling examined three outcomes: admission to hospital; admission to an intensive care unit (ICU) and death. Deprivation increased the likelihood of contracting COVID-19 in all age groups and across all pandemic waves, except for the 20-39 age group. Deprivation, age, comorbidity and male gender carried increased risk of hospital admission. Deprivation was not a factor in predicting ICU admission or death, and diagnosis in wave 2 was associated with the lowest risk of all three outcomes. Our study suggests that COVID-19 spreads easily through all strata of society and particularly in the more deprived population; however this was not a consistent finding. Ireland is ethnically more homogenous than other countries reporting a larger deprivation gradient, and in such societies, structural racial differences may contribute more to poor COVID outcomes than elements of deprivation.

Sections du résumé

BACKGROUND
Since the pandemic onset, deprivation has been seen as a significant determinant of COVID-19 incidence and mortality. This study explores outcomes of COVID-19 in the context of material deprivation across three pandemic waves in Ireland.
METHODS
Between 1st March 2020 and 13th May 2021, 252,637 PCR-confirmed COVID-19 cases were notified in Ireland. Cases were notified to the national Computerised Infectious Disease Reporting (CIDR) system. Each case was geo-referenced and assigned a deprivation category according to the Haase-Pratschke (HP) Deprivation Index. Regression modelling examined three outcomes: admission to hospital; admission to an intensive care unit (ICU) and death.
RESULTS
Deprivation increased the likelihood of contracting COVID-19 in all age groups and across all pandemic waves, except for the 20-39 age group. Deprivation, age, comorbidity and male gender carried increased risk of hospital admission. Deprivation was not a factor in predicting ICU admission or death, and diagnosis in wave 2 was associated with the lowest risk of all three outcomes.
CONCLUSIONS
Our study suggests that COVID-19 spreads easily through all strata of society and particularly in the more deprived population; however this was not a consistent finding. Ireland is ethnically more homogenous than other countries reporting a larger deprivation gradient, and in such societies, structural racial differences may contribute more to poor COVID outcomes than elements of deprivation.

Identifiants

pubmed: 37478117
doi: 10.1371/journal.pone.0287636
pii: PONE-D-22-14948
pmc: PMC10361474
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0287636

Informations de copyright

Copyright: © 2023 McKeown et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Declan McKeown (D)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

Angela McCourt (A)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

Louise Hendrick (L)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

Anne O'Farrell (A)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

Fionnuala Donohue (F)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

Laurin Grabowsky (L)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

Paul Kavanagh (P)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

Patricia Garvey (P)

Health Protection Surveillance Centre, Health Service Executive, Dublin, Ireland.

Joan O'Donnell (J)

Health Protection Surveillance Centre, Health Service Executive, Dublin, Ireland.

Lois O'Connor (L)

Health Protection Surveillance Centre, Health Service Executive, Dublin, Ireland.

John Cuddihy (J)

Health Protection Surveillance Centre, Health Service Executive, Dublin, Ireland.

Matt Robinson (M)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

Declan O'Reilly (D)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

Anthony Staines (A)

School of Nursing, Psychotherapy and Community Health, Dublin City University, Dublin, Ireland.

Howard Johnson (H)

National Health Intelligence Unit, Health Service Executive, Dublin, Ireland.

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