Scalable biomimetic sensing system with membrane receptor dual-monolayer probe and graphene transistor arrays.
Journal
Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440
Informations de publication
Date de publication:
21 07 2023
21 07 2023
Historique:
medline:
23
10
2023
pubmed:
21
7
2023
entrez:
21
7
2023
Statut:
ppublish
Résumé
Affinity-based biosensing can enable point-of-care diagnostics and continuous health monitoring, which commonly follows bottom-up approaches and is inherently constrained by bioprobes' intrinsic properties, batch-to-batch consistency, and stability in biofluids. We present a biomimetic top-down platform to circumvent such difficulties by combining a "dual-monolayer" biorecognition construct with graphene-based field-effect-transistor arrays. The construct adopts redesigned water-soluble membrane receptors as specific sensing units, positioned by two-dimensional crystalline S-layer proteins as dense antifouling linkers guiding their orientations. Hundreds of transistors provide statistical significance from transduced signals. System feasibility was demonstrated with rSbpA-ZZ/CXCR4
Identifiants
pubmed: 37478177
doi: 10.1126/sciadv.adf1402
pmc: PMC10361598
doi:
Substances chimiques
Graphite
7782-42-5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
eadf1402Références
Nat Rev Immunol. 2002 Feb;2(2):106-15
pubmed: 11910892
J Med Life. 2009 Apr-Jun;2(2):196-8
pubmed: 20108540
Biochem Soc Trans. 2016 Jun 15;44(3):790-5
pubmed: 27284043
Curr Opin Biotechnol. 2011 Dec;22(6):824-31
pubmed: 21696943
Lab Chip. 2013 May 7;13(9):1780-9
pubmed: 23478879
Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14633-14638
pubmed: 27930344
ACS Nano. 2016 Jun 28;10(6):6173-9
pubmed: 27227361
Front Chem. 2021 Jun 02;9:587142
pubmed: 34150714
Life (Basel). 2021 Nov 24;11(12):
pubmed: 34947816
ACS Nano. 2011 Jul 26;5(7):5408-16
pubmed: 21696137
2d Mater. 2020 Jan;7(1):
pubmed: 32523701
ACS Appl Mater Interfaces. 2018 May 9;10(18):16169-16176
pubmed: 29641171
Nat Methods. 2022 Jun;19(6):679-682
pubmed: 35637307
Sci Adv. 2021 Sep 17;7(38):eabg8387
pubmed: 34524851
Biosens Bioelectron. 2021 Jan 1;171:112621
pubmed: 33120234
Angew Chem Int Ed Engl. 1999;38(8):1034-54
pubmed: 25138491
Front Vet Sci. 2018 Mar 29;5:56
pubmed: 29651421
Prog Mol Biol Transl Sci. 2011;103:277-352
pubmed: 21999999
Methods Mol Biol. 2020;2073:195-218
pubmed: 31612444
Front Neurosci. 2017 Oct 24;11:590
pubmed: 29123467
Sci Rep. 2020 Dec 7;10(1):21371
pubmed: 33288780
Nat Immunol. 2004 Sep;5(9):943-52
pubmed: 15300245
Sci Rep. 2017 Apr 21;7(1):1032
pubmed: 28432329
Appl Environ Microbiol. 2002 Jul;68(7):3251-60
pubmed: 12089001
Cold Spring Harb Protoc. 2019 Feb 1;2019(2):
pubmed: 30710025
Bioconjug Chem. 2004 May-Jun;15(3):664-71
pubmed: 15149195
Nat Nanotechnol. 2019 Dec;14(12):1143-1149
pubmed: 31712665
Appl Environ Microbiol. 2004 Mar;70(3):1514-21
pubmed: 15006773
Viruses. 2010 Feb;2(2):574-600
pubmed: 21994649
Adv Cancer Res. 2014;124:31-82
pubmed: 25287686
J Oral Biol Craniofac Res. 2016 May-Aug;6(2):153-9
pubmed: 27195214
FEMS Microbiol Rev. 2014 Sep;38(5):823-64
pubmed: 24483139
Cell. 2022 Jun 23;185(13):2234-2247.e17
pubmed: 35709748
Nat Commun. 2020 Nov 10;11(1):5689
pubmed: 33173041
Colloids Surf B Biointerfaces. 2015 Apr 1;128:132-139
pubmed: 25734967
Chem Rev. 2016 Jan 13;116(1):215-57
pubmed: 26691648
Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14646-51
pubmed: 12417763
Adv Mater. 2022 Sep;34(36):e2203224
pubmed: 35853614
Immunol Cell Biol. 2001 Aug;79(4):340-4
pubmed: 11488980
Nano Lett. 2014 May 14;14(5):2709-14
pubmed: 24742304
QRB Discov. 2020 Apr 09;1:e4
pubmed: 34192260
Analyst. 2016 Apr 25;141(9):2704-11
pubmed: 26788552
Nat Commun. 2022 Aug 27;13(1):5064
pubmed: 36030295
Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8652-E8659
pubmed: 30154163
Sensors (Basel). 2019 Sep 28;19(19):
pubmed: 31569330
Chem Rev. 2022 Sep 28;122(18):14085-14179
pubmed: 35921495
Nature. 2001 Mar 1;410(6824):50-6
pubmed: 11242036
Nat Biomed Eng. 2021 Jul;5(7):666-677
pubmed: 34031558
Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25668-25676
pubmed: 31776256
Chem Rev. 2019 Jan 9;119(1):36-93
pubmed: 30372041
Trends Biochem Sci. 2020 Aug;45(8):639-649
pubmed: 32402748
Heliyon. 2018 Mar 01;4(3):e00557
pubmed: 29560468