Incidence, risk factors, and clinical findings of syphilis among men living with HIV in Croatia during the COVID-19 pandemic.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
21 07 2023
21 07 2023
Historique:
received:
14
03
2023
accepted:
14
07
2023
medline:
23
10
2023
pubmed:
22
7
2023
entrez:
21
7
2023
Statut:
epublish
Résumé
We conducted a nationwide longitudinal observational study to estimate the incidence of syphilis in a cohort of male persons living with HIV (MLWH) in Croatia in the pre-COVID-19 and COVID-19 years. Data were reviewed and extracted from the clinical database. We analyzed 1187 MLWH (≥ 18 years) in care in Croatia from 2018 to 2021 and used Poisson regression to calculate rates. We observed a 91.4% increase in incidence between 2019 and 2020; the overall rate was 6.0/100 person-years, and the annual rate ranged from 3.3/100 person-years in 2018 to 9.3/100 person-years in 2021. We found higher rates in men who have sex with men, MLWH with a baseline history of syphilis, MLWH with a more recent HIV diagnosis, and a lower rate in those who had clinical AIDS. The rate of syphilis serological testing was 3.5% lower in 2020 compared to 2019. Recurrent syphilis was more likely asymptomatic compared to the first episodes. In conclusion, during the COVID-19 epidemic years, there was a huge increase in syphilis. Results highlight the need for enhanced and novel prevention interventions.
Identifiants
pubmed: 37479770
doi: 10.1038/s41598-023-38807-1
pii: 10.1038/s41598-023-38807-1
pmc: PMC10361976
doi:
Types de publication
Observational Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
11784Informations de copyright
© 2023. The Author(s).
Références
J Acquir Immune Defic Syndr. 2011 Dec 1;58(4):408-16
pubmed: 21857351
J Acquir Immune Defic Syndr. 2021 Feb 1;86(2):219-223
pubmed: 33433124
Clin Dermatol. 2021 Jul-Aug;39(4):710-713
pubmed: 34809778
Sex Transm Infect. 2019 Aug;95(5):336-341
pubmed: 31010954
J Infect Dis. 2021 Sep 1;224(5):798-803
pubmed: 34134130
Sex Transm Infect. 2015 Dec;91(8):564-8
pubmed: 26163510
Clin Infect Dis. 2022 Mar 1;74(4):e1-e5
pubmed: 33999990
Lancet Glob Health. 2021 Aug;9(8):e1110-e1118
pubmed: 34246332
Lancet Infect Dis. 2018 Mar;18(3):308-317
pubmed: 29229440
J Eur Acad Dermatol Venereol. 2020 Oct;34(10):e553-e556
pubmed: 32491214
Open Forum Infect Dis. 2022 Nov 16;9(12):ofac592
pubmed: 36504700
Sex Transm Infect. 2022 May;98(3):231
pubmed: 34039745
Clin Infect Dis. 2018 Nov 13;67(11):1750-1759
pubmed: 29688270
PLoS One. 2016 Dec 16;11(12):e0168642
pubmed: 27992604
Croat Med J. 2021 Dec 31;62(6):542-552
pubmed: 34981686
J Travel Med. 2020 Dec 23;27(8):
pubmed: 33152761
Sex Transm Dis. 2021 Jun 1;48(6):e81-e83
pubmed: 33783406
Front Public Health. 2021 Dec 16;9:737817
pubmed: 34976912
Clin Infect Dis. 2022 Aug 31;75(3):483-492
pubmed: 34788808
Infect Dis (Auckl). 2019 Oct 16;12:1178633719883282
pubmed: 31666795
Arch Sex Behav. 2023 Feb;52(2):783-791
pubmed: 36175816
Sex Transm Infect. 2017 Aug;93(5):323-326
pubmed: 27856515
Medicine (Baltimore). 2017 Jan;96(2):e5849
pubmed: 28079818
BMC Infect Dis. 2015 Aug 20;15:356
pubmed: 26289937
AIDS Behav. 2008 Jul;12(4 Suppl):S86-92
pubmed: 18543093
Przegl Epidemiol. 2021;75(2):151-158
pubmed: 34696547
Int J Infect Dis. 2023 Mar;128:265-271
pubmed: 36642212
Sex Transm Infect. 2022 Mar;98(2):150-151
pubmed: 33737449
Ann Med Surg (Lond). 2022 Aug;80:104239
pubmed: 35937637
MMWR Morb Mortal Wkly Rep. 2001 Feb 23;50(7):117-20
pubmed: 11393490
Am J Public Health. 2013 Aug;103(8):1450-6
pubmed: 23153138
PLoS One. 2022 May 19;17(5):e0268670
pubmed: 35587482
Nurs Clin North Am. 2020 Sep;55(3):361-377
pubmed: 32762856
Public Health Pract (Oxf). 2021 Nov;2:100072
pubmed: 33521735
Sex Transm Infect. 2021 Mar;97(2):101-102
pubmed: 33132224
Sci Rep. 2019 Nov 21;9(1):17307
pubmed: 31754119
Open Forum Infect Dis. 2023 Jan 12;10(2):ofad017
pubmed: 36751651
Sex Transm Infect. 2021 Jun;97(4):319
pubmed: 33082234
N Engl J Med. 2023 Apr 6;388(14):1296-1306
pubmed: 37018493
Sex Transm Infect. 2022 Feb;98(1):70
pubmed: 33653880
Open Forum Infect Dis. 2018 Apr 28;5(6):ofy096
pubmed: 29977956
Sex Transm Infect. 2021 Mar;97(2):99
pubmed: 32796092
Sex Transm Infect. 2012 Nov;88(7):539-44
pubmed: 22628664
Int J Environ Res Public Health. 2022 Aug 05;19(15):
pubmed: 35954984
Am J Public Health. 2012 Jan;102(1):e1-8
pubmed: 22095364
Sex Transm Infect. 2022 Feb;98(1):72
pubmed: 34544886