Structure elucidation of Keroplatus (Diptera:Keroplatidae) fungus gnat oxyluciferin.

Bioluminescence Keroplatidae Keroplatus NMR spectroscopy Orfelia fultoni Oxyluciferin

Journal

Biochemical and biophysical research communications
ISSN: 1090-2104
Titre abrégé: Biochem Biophys Res Commun
Pays: United States
ID NLM: 0372516

Informations de publication

Date de publication:
08 Oct 2023
Historique:
received: 11 07 2023
revised: 14 07 2023
accepted: 15 07 2023
pubmed: 23 7 2023
medline: 23 7 2023
entrez: 22 7 2023
Statut: ppublish

Résumé

Bioluminescence of insects is a well-known natural phenomenon in the focus of interest of scientific research. While the mechanisms of bioluminescence in Coleoptera have been extensively studied, there is a lack of information about the chemistry of light emission in Diptera species. Here we report the Keroplatus spp. oxyluciferin structure elucidation and identification as 3-hydroxykynurenic acid. Additionally, the present study provides the first direct evidence of the relationship between the bioluminescent systems of Orfelia and Keroplatus. However, the properties of the putative Orfelia oxyluciferin suggest that the light emission mechanisms are not identical.

Identifiants

DOI: 10.1016/j.bbrc.2023.07.035 PMID: 37480687
pubmed: 37480687
pii: S0006-291X(23)00892-6
doi: 10.1016/j.bbrc.2023.07.035
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-5

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

Auteurs

Alexey A Kotlobay (AA)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia. Electronic address: alexey_kotlobay@ibch.ru.

Maxim A Dubinnyi (MA)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology (State University), 9 Institutskiy per., Dolgoprudny, Moscow, 141700, Russia.

Sergey I Kovalchuk (SI)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia.

Aleksandr P Makhin (AP)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia; Higher Chemical College of the Russian Academy of Sciences, D. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya sq., Moscow, 125047, Russia.

Vasily S Miturich (VS)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia; Faculty of Chemistry, National Research University Higher School of Economics, 7 Vavilova str., Moscow, 119048, Russia.

Maria S Lyakhovich (MS)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia.

Danielle M Fontaine (DM)

Department of Chemistry, Connecticut College, New London, CT, 06320, USA.

Tara L Southworth (TL)

Department of Chemistry, Connecticut College, New London, CT, 06320, USA.

Vladimir I Shmygarev (VI)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia.

Oleg N Yatskin (ON)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia.

Bruce R Branchini (BR)

Department of Chemistry, Connecticut College, New London, CT, 06320, USA.

Ilia V Yampolsky (IV)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia; Institute of Translational Medicine, Pirogov Russian National Research Medical University, 1 Ostrovityanova str., Moscow, 117997, Russia.

Zinaida M Kaskova (ZM)

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 16/10 Miklukho-Maklaya str., Moscow, 117997, Russia; Institute of Translational Medicine, Pirogov Russian National Research Medical University, 1 Ostrovityanova str., Moscow, 117997, Russia. Electronic address: zkaskova@ibch.ru.

Classifications MeSH