Cutaneous metastasis as a first presentation of lung carcinoma: a case series.
Immunohistochemistry
Lung carcinoma
Pathology
Prognosis
Skin metastasis
Journal
Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382
Informations de publication
Date de publication:
23 Jul 2023
23 Jul 2023
Historique:
received:
29
03
2023
accepted:
06
06
2023
medline:
24
7
2023
pubmed:
23
7
2023
entrez:
22
7
2023
Statut:
epublish
Résumé
Cutaneous metastases (CM) revealing lung carcinoma are extremely rare, accounting for 0.8%. The diagnosis is guided by histology and immunohistochemistry. Treatment is palliative. The prognosis is poor. This is a retrospective study of the available clinical and histological records of four North African patients with CM revealing lung cancer treated at our institute between 2004 and 2010. Three men and one woman were registered. The mean age was 54.5 years (38-74 years). Two patients had primary adenocarcinoma, one patient had small cell carcinoma and one had squamous cell carcinoma. Treatment was based on chemotherapy in two cases and antalgic radiotherapy in two cases, one patient underwent surgical resection as the lesion was infected. The overall survival after diagnosis was between one and four months. A skin nodule can be the first symptom revealing lung cancer. A rare clinical presentation that should not be taken for a benign nodule, the biopsy and histological study with immunohistochemistry confirm the diagnosis.
Identifiants
pubmed: 37481539
doi: 10.1186/s13256-023-04029-2
pii: 10.1186/s13256-023-04029-2
pmc: PMC10363314
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
315Informations de copyright
© 2023. The Author(s).
Références
BMJ Case Rep. 2014 Sep 22;2014:
pubmed: 25246468
Clin Cosmet Investig Dermatol. 2022 Sep 12;15:1869-1872
pubmed: 36117767
Case Rep Oncol. 2019 Jun 26;12(2):480-487
pubmed: 31320871
N Am J Med Sci. 2016 May;8(5):222-5
pubmed: 27298817
Case Rep Oncol. 2022 Nov 10;15(3):1034-1038
pubmed: 36605228
Stem Cell Investig. 2014 Mar 05;1:6
pubmed: 27358853
Clin Case Rep. 2019 Jul 25;7(9):1796-1797
pubmed: 31534754
Int J Surg Case Rep. 2017;41:327-331
pubmed: 29136605
Onco Targets Ther. 2020 Dec 23;13:13143-13149
pubmed: 33380804
Indian J Dermatol. 2015 Mar-Apr;60(2):213
pubmed: 25814739