Lung abscess by
Fusobacterium nucleatum
Streptococcus spp.
co-infection
lung abscess
shotgun metagenome next-generation sequencing
Journal
Open life sciences
ISSN: 2391-5412
Titre abrégé: Open Life Sci
Pays: Poland
ID NLM: 101669614
Informations de publication
Date de publication:
2023
2023
Historique:
received:
14
02
2023
revised:
15
05
2023
accepted:
05
06
2023
medline:
24
7
2023
pubmed:
24
7
2023
entrez:
24
7
2023
Statut:
epublish
Résumé
A lung abscess is a necrotizing infection caused by microbiomes that lead to the loss of healthy lung tissue. The routine culture is a waste of time and yields false-negative results, and clinicians could only choose empiric therapy or use broad-spectrum antibiotics, which could significantly contribute to the problem of resistance or aggravate the condition. We report three patients with a routine-culture-negative lung abscess. The presenting symptoms included fever, cough, dyspnea, and chest pain, and a computed tomography scan revealed a lesion in the lungs. The bronchoalveolar lavage fluid and pleural fluid were tested for pathogens using metagenome next-generation sequencing (mNGS), and the results revealed
Identifiants
pubmed: 37483431
doi: 10.1515/biol-2022-0651
pii: biol-2022-0651
pmc: PMC10358748
doi:
Types de publication
Case Reports
Langues
eng
Pagination
20220651Informations de copyright
© 2023 the author(s), published by De Gruyter.
Déclaration de conflit d'intérêts
Conflict of interest: Xiaolin Liu is employed by the company Liaoning Kanghui Biotechnology Co., Ltd. All authors declare that they have no conflict of interest.
Références
Mol Microbiol. 2009 Jan;71(1):35-47
pubmed: 19007407
Nat Rev Microbiol. 2019 Mar;17(3):156-166
pubmed: 30546113
BMC Infect Dis. 2020 May 18;20(1):351
pubmed: 32423417
Ann Transplant. 2021 Jun 08;26:e931059
pubmed: 34099614
Intern Med. 2022 Jul 15;61(14):2227-2232
pubmed: 34980794
J Bras Pneumol. 2006 Mar-Apr;32(2):136-43
pubmed: 17273583
J Osteopath Med. 2022 Jul 14;122(10):493-497
pubmed: 35822717
Eur Radiol. 2022 Feb;32(2):1184-1194
pubmed: 34327579
Am J Ther. 2014 May-Jun;21(3):217-21
pubmed: 22248872
Microbes Infect. 2000 Oct;2(12):1425-30
pubmed: 11099928
Microbiol Immunol. 1999;43(3):207-16
pubmed: 10338189
N Engl J Med. 2014 Jun 19;370(25):2408-17
pubmed: 24896819
Thorac Surg Clin. 2022 Aug;32(3):349-360
pubmed: 35961743
Arch Pathol Lab Med. 2017 Jun;141(6):776-786
pubmed: 28169558
CMAJ. 2022 May 9;194(18):E645-E648
pubmed: 35534028
Ann Transl Med. 2015 Aug;3(13):183
pubmed: 26366400
PLoS One. 2018 Apr 17;13(4):e0194648
pubmed: 29664913
J Periodontal Res. 2013 Aug;48(4):493-9
pubmed: 23173872
Clin Microbiol Rev. 2023 Mar 23;36(1):e0011922
pubmed: 36847515
Curr Opin Microbiol. 2015 Feb;23:141-7
pubmed: 25576662
ANZ J Surg. 2022 Jul;92(7-8):1850-1855
pubmed: 35678219
Eur J Clin Microbiol Infect Dis. 2017 Feb;36(2):329-336
pubmed: 27771780
Adv Respir Med. 2023 Feb 02;91(1):49-65
pubmed: 36825940
BMC Pulm Med. 2020 Mar 17;20(1):65
pubmed: 32178660
Pneumonol Alergol Pol. 2014;82(3):276-85
pubmed: 24793153
Ophthalmology. 2017 Aug;124(8):1247-1248
pubmed: 28526549