Determination of scopolamine and butylscopolamine in beverages, urine and Buscopan® tablets samples using electrophoresis microchip with integrated contactless conductivity detection.
Electrochemical detection
Forensic chemistry
Microfluidics
Predatory drugs
Tropane alkaloids
Journal
Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R
Informations de publication
Date de publication:
01 Jan 2024
01 Jan 2024
Historique:
received:
26
03
2023
revised:
16
06
2023
accepted:
15
07
2023
medline:
20
9
2023
pubmed:
24
7
2023
entrez:
24
7
2023
Statut:
ppublish
Résumé
The number of cases in which scopolamine (SCO) was used for both recreational and predatory purposes has increased dramatically in recent decades. Linked to this, there is a concern about obtaining SCO through thermal degradation of butylscopolamine (BSCO) - an active ingredient of Buscopan® - a drug sold without a medical prescription. In this study, mixtures containing SCO and BSCO were separated and detected on a microchip electrophoresis (ME) device with integrated capacitively coupled contactless conductivity detection (C
Identifiants
pubmed: 37487267
pii: S0039-9140(23)00711-7
doi: 10.1016/j.talanta.2023.124960
pii:
doi:
Substances chimiques
Butylscopolammonium Bromide
2Z3E1OF81V
Scopolamine
DL48G20X8X
Tablets
0
Butyric Acid
107-92-6
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
124960Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.