Multidirectional characterization of cellular composition and spatial architecture in human multiple primary lung cancers.
Journal
Cell death & disease
ISSN: 2041-4889
Titre abrégé: Cell Death Dis
Pays: England
ID NLM: 101524092
Informations de publication
Date de publication:
25 07 2023
25 07 2023
Historique:
received:
31
01
2023
accepted:
13
07
2023
revised:
10
07
2023
medline:
26
7
2023
pubmed:
25
7
2023
entrez:
24
7
2023
Statut:
epublish
Résumé
Multiple primary lung cancers (MPLCs) pose diagnostic and therapeutic challenges in clinic. Here, we orchestrated the cellular and spatial architecture of MPLCs by combining single-cell RNA-sequencing and spatial transcriptomics. Notably, we identified a previously undescribed sub-population of epithelial cells termed as CLDN2
Identifiants
pubmed: 37488117
doi: 10.1038/s41419-023-05992-w
pii: 10.1038/s41419-023-05992-w
pmc: PMC10366158
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
462Informations de copyright
© 2023. The Author(s).
Références
Dev Cell. 2018 Mar 26;44(6):653-654
pubmed: 29587138
Nat Commun. 2021 May 11;12(1):2582
pubmed: 33976133
Pathologica. 2018 Mar;110(1):5-11
pubmed: 30259909
J Thorac Oncol. 2020 Feb;15(2):203-215
pubmed: 31634666
Nat Methods. 2017 Oct;14(10):979-982
pubmed: 28825705
Medicine (Baltimore). 2018 Dec;97(52):e13817
pubmed: 30593175
Cancer Prev Res (Phila). 2017 Sep;10(9):491-493
pubmed: 28821543
Eur Respir J. 2016 Mar;47(3):720-3
pubmed: 26929315
Cancer Res. 2007 Feb 15;67(4):1744-9
pubmed: 17308116
J Cancer Res Clin Oncol. 2018 Apr;144(4):743-749
pubmed: 29392402
Cancer Res. 2021 Dec 15;81(24):6087-6089
pubmed: 34911777
J Thorac Oncol. 2015 Sep;10(9):1243-1260
pubmed: 26291008
Cancer Manag Res. 2020 Oct 20;12:10361-10374
pubmed: 33116891
J Clin Pathol. 2017 Mar;70(3):202-207
pubmed: 27445341
J Thorac Dis. 2018 Feb;10(2):1058-1066
pubmed: 29607181
Cell. 2017 Jun 1;169(6):1000-1011
pubmed: 28575665
J Cell Physiol. 2011 Jun;226(6):1471-8
pubmed: 20717932
Histopathology. 2017 Mar;70(4):595-621
pubmed: 27775850
Nat Med. 2020 Feb;26(2):259-269
pubmed: 32042191
Cancer Cell Int. 2018 Oct 17;18:160
pubmed: 30349422
OMICS. 2012 May;16(5):284-7
pubmed: 22455463
Nat Cancer. 2022 Jan;3(1):108-121
pubmed: 35121991
Int J Mol Sci. 2021 Jan 06;22(2):
pubmed: 33419064
J Thorac Oncol. 2016 May;11(5):651-665
pubmed: 26944304
FASEB J. 2020 Nov;34(11):14820-14831
pubmed: 32910505
Nat Med. 2019 May;25(5):759-766
pubmed: 31036879
Clin Cancer Res. 2019 Dec 1;25(23):7113-7125
pubmed: 31471310
Oncol Lett. 2021 Apr;21(4):322
pubmed: 33692854
Nat Commun. 2020 May 8;11(1):2285
pubmed: 32385277
J Exp Clin Cancer Res. 2018 Aug 17;37(1):195
pubmed: 30119639
Nat Commun. 2021 Feb 17;12(1):1088
pubmed: 33597522
Cell. 2020 Sep 3;182(5):1232-1251.e22
pubmed: 32822576
N Engl J Med. 2015 May 21;372(21):2018-28
pubmed: 25891174
N Engl J Med. 2018 Aug 30;379(9):e14
pubmed: 30179394
Cancer Res. 2014 Nov 1;74(21):6071-81
pubmed: 25189529
CA Cancer J Clin. 2021 Jan;71(1):7-33
pubmed: 33433946
Nat Med. 2018 Jul;24(7):978-985
pubmed: 29942094
ESMO Open. 2020 Aug;4(Suppl 3):e000738
pubmed: 32817129
Biomaterials. 2021 Feb;269:120648
pubmed: 33445099
N Engl J Med. 2019 Nov 21;381(21):2020-2031
pubmed: 31562796
Cancer Cell. 2021 Dec 13;39(12):1594-1609.e12
pubmed: 34767762
Sci Immunol. 2018 Nov 2;3(29):
pubmed: 30389797
J Oncol. 2021 Jul 9;2021:9924473
pubmed: 34306081
Cell. 2019 Jun 13;177(7):1888-1902.e21
pubmed: 31178118
Cancer Lett. 2020 Jan 1;468:82-87
pubmed: 31600530
J Clin Oncol. 2018 Mar 1;36(7):633-641
pubmed: 29337640
Biochim Biophys Acta. 2012 Aug;1826(1):44-52
pubmed: 22465409
Histopathology. 2017 Sep;71(3):425-436
pubmed: 28401582
Clin Cancer Res. 2019 Aug 1;25(15):4712-4722
pubmed: 31028088