Bioarchaeological and paleogenomic profiling of the unusual Neolithic burial from Grotta di Pietra Sant'Angelo (Calabria, Italy).
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
24 07 2023
24 07 2023
Historique:
received:
27
01
2023
accepted:
21
07
2023
medline:
26
7
2023
pubmed:
25
7
2023
entrez:
24
7
2023
Statut:
epublish
Résumé
The Neolithic burial of Grotta di Pietra Sant'Angelo (CS) represents a unique archaeological finding for the prehistory of Southern Italy. The unusual placement of the inhumation at a rather high altitude and far from inhabited areas, the lack of funerary equipment and the prone deposition of the body find limited similarities in coeval Italian sites. These elements have prompted wider questions on mortuary customs during the prehistory of Southern Italy. This atypical case requires an interdisciplinary approach aimed to build an integrated bioarchaeological profile of the individual. The paleopathological investigation of the skeletal remains revealed the presence of numerous markers that could be associated with craft activities, suggesting possible interpretations of the individual's lifestyle. CT analyses, carried out on the maxillary bones, showed the presence of a peculiar type of dental wear, but also a good density of the bone matrix. Biomolecular and micromorphological analyses of dental calculus highlight the presence of a rich Neolithic-like oral microbiome, the composition of which is consistent with the presence pathologies. Finally, paleogenomic data obtained from the individual were compared with ancient and modern Mediterranean populations, including unpublished high-resolution genome-wide data for 20 modern inhabitants of the nearby village of San Lorenzo Bellizzi, which provided interesting insights into the biodemographic landscape of the Neolithic in Southern Italy.
Identifiants
pubmed: 37488251
doi: 10.1038/s41598-023-39250-y
pii: 10.1038/s41598-023-39250-y
pmc: PMC10366206
doi:
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
11978Informations de copyright
© 2023. The Author(s).
Références
Am J Phys Anthropol. 2000 May;112(1):39-48
pubmed: 10766942
Nat Ecol Evol. 2018 Mar;2(3):520-528
pubmed: 29335577
Commun Biol. 2022 Nov 18;5(1):1262
pubmed: 36400919
Am J Phys Anthropol. 1977 Sep;47(2):355-6
pubmed: 910890
Biochemistry (Mosc). 2022 Mar;87(3):242-258
pubmed: 35526849
Am J Phys Anthropol. 1969 Mar;30(2):297-301
pubmed: 5772048
Mol Biol Evol. 2018 Jun 1;35(6):1547-1549
pubmed: 29722887
Bioinformatics. 2009 Jul 15;25(14):1754-60
pubmed: 19451168
J Hered. 2021 May 24;112(3):241-249
pubmed: 33768239
Am J Phys Anthropol. 1985 Aug;67(4):393-402
pubmed: 4061592
Sci Rep. 2017 May 16;7(1):1984
pubmed: 28512355
BMC Res Notes. 2016 Feb 12;9:88
pubmed: 26868221
Nat Methods. 2012 Jul 30;9(8):772
pubmed: 22847109
Science. 1994 Jun 17;264(5166):1775-8
pubmed: 8209259
Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):
pubmed: 34312252
Am J Phys Anthropol. 2001 May;115(1):50-6
pubmed: 11309749
Genome Res. 2021 Mar;31(3):472-483
pubmed: 33579752
Genome Biol. 2022 Dec 13;23(1):250
pubmed: 36510283
Sci Adv. 2019 Sep 04;5(9):eaaw3492
pubmed: 31517044
Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):486-91
pubmed: 21187393
PLoS One. 2016 Oct 5;11(10):e0163019
pubmed: 27706187
Sci Rep. 2016 Jan 14;6:18932
pubmed: 26764605
Nat Commun. 2020 Feb 24;11(1):939
pubmed: 32094358
Nat Commun. 2012 Feb 28;3:698
pubmed: 22426219
Nat Biotechnol. 2008 Dec;26(12):1367-72
pubmed: 19029910
Commun Biol. 2022 Jun 7;5(1):554
pubmed: 35672445
ISME J. 2013 May;7(5):1016-25
pubmed: 23303375
Expert Rev Anti Infect Ther. 2016 Jun;14(6):539-45
pubmed: 27124204
iScience. 2022 Apr 12;25(5):104244
pubmed: 35494246
Nat Protoc. 2014 May;9(5):1056-82
pubmed: 24722405
Biology (Basel). 2021 Dec 14;10(12):
pubmed: 34943238
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2229-34
pubmed: 24469802
Nature. 2016 May 02;534(7606):200-5
pubmed: 27135931
PLoS Genet. 2014 May 08;10(5):e1004353
pubmed: 24809476
Sci Rep. 2022 May 26;12(1):6468
pubmed: 35618734
Sci Adv. 2021 Sep 24;7(39):eabi7673
pubmed: 34559560
Am J Phys Anthropol. 1985 Sep;68(1):15-28
pubmed: 4061599
Bioinformatics. 2013 Jul 01;29(13):1682-4
pubmed: 23613487
Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10298-303
pubmed: 27573829
J Proteomics. 2020 Sep 15;227:103920
pubmed: 32712371
Sci Rep. 2018 Jun 29;8(1):9822
pubmed: 29959351
Commun Biol. 2021 Feb 5;4(1):169
pubmed: 33547403
Nat Ecol Evol. 2018 May;2(5):791-799
pubmed: 29581591
Microbiome. 2019 Jul 6;7(1):102
pubmed: 31279340
PLoS Biol. 2019 Jul 30;17(7):e3000166
pubmed: 31361744
Science. 2019 Nov 8;366(6466):708-714
pubmed: 31699931
Am J Phys Anthropol. 1986 Apr;69(4):427-35
pubmed: 3717320
Nature. 2017 Nov 16;551(7680):368-372
pubmed: 29144465
Nat Commun. 2018 Nov 20;9(1):4744
pubmed: 30459334
PLoS One. 2020 Dec 21;15(12):e0243369
pubmed: 33347451
Infect Agent Cancer. 2019 Jan 30;14:3
pubmed: 30728854
Am J Phys Anthropol. 1984 Jan;63(1):39-56
pubmed: 6422767
Adv Appl Microbiol. 2016;97:171-210
pubmed: 27926431
Nucleic Acids Res. 2016 Jul 8;44(W1):W58-63
pubmed: 27084951
Nature. 2015 Dec 24;528(7583):499-503
pubmed: 26595274
Am J Phys Anthropol. 1996 Sep;101(1):101-13
pubmed: 8876816
Nat Genet. 2014 Apr;46(4):336-44
pubmed: 24562188
Quat Int. 2023 Apr 20;653-654:3-18
pubmed: 37089908
Nat Commun. 2020 Sep 16;11(1):4759
pubmed: 32938921
PLoS One. 2020 Jan 28;15(1):e0227433
pubmed: 31990948
Genome Biol. 2019 Dec 16;20(1):280
pubmed: 31842945
Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):6886-91
pubmed: 27274049
BMC Bioinformatics. 2014 Nov 25;15:356
pubmed: 25420514
Am J Hum Genet. 2007 Sep;81(3):559-75
pubmed: 17701901
Sci Rep. 2016 Sep 01;6:32513
pubmed: 27582244
Microorganisms. 2019 Oct 09;7(10):
pubmed: 31600905
Sci Rep. 2022 Sep 27;12(1):16139
pubmed: 36168035
Sci Rep. 2021 Dec 14;11(1):23735
pubmed: 34907203
PLoS One. 2014 Jul 16;9(7):e100808
pubmed: 25028938
Nat Ecol Evol. 2020 Mar;4(3):334-345
pubmed: 32094539
Nurs Clin North Am. 2019 Jun;54(2):297-311
pubmed: 31027668
J Investig Clin Dent. 2015 Feb;6(1):25-31
pubmed: 23857867
NPJ Biofilms Microbiomes. 2017 Oct 2;3:23
pubmed: 28979798
Hum Mutat. 2013 Sep;34(9):1189-94
pubmed: 23696374
Mol Biol Evol. 2022 Feb 3;39(2):
pubmed: 35038748
Proc Natl Acad Sci U S A. 2021 May 18;118(20):
pubmed: 33972424
Sci Rep. 2021 Feb 4;11(1):3045
pubmed: 33542324
Bioinformatics. 2010 Mar 15;26(6):841-2
pubmed: 20110278
Trends Genet. 2017 Aug;33(8):508-520
pubmed: 28688671
Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):
pubmed: 33419922
Br Dent J. 2014 Oct;217(8):433-7
pubmed: 25342350
Genome Biol. 2015 Oct 12;16:224
pubmed: 26458810
Genes (Basel). 2021 Apr 25;12(5):
pubmed: 33922908
Biomed Rep. 2019 Nov;11(5):199-206
pubmed: 31632667