Neuroimaging Features in Children with Optic Nerve Hypoplasia and Septo-Optic-Pituitary Dysplasia.
MRI
neuronal migration disorders
optic nerve hypoplasia
pediatrics
pituitary gland
septo-optic dysplasia
septum pellucidum
Journal
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
ISSN: 0317-1671
Titre abrégé: Can J Neurol Sci
Pays: England
ID NLM: 0415227
Informations de publication
Date de publication:
26 Jul 2023
26 Jul 2023
Historique:
pubmed:
26
7
2023
medline:
26
7
2023
entrez:
26
7
2023
Statut:
aheadofprint
Résumé
Optic nerve hypoplasia (ONH) and septo-optic-pituitary dysplasia (SOD) are common causes of congenital visual impairment. Our primary aim was to investigate the prevalence of abnormal neuroimaging features in patients with these disorders in Manitoba, Canada, and compare them with published reports. A retrospective neuroimaging review was performed in patients resident in Manitoba with ONH/SOD. There were 128 patients ( The prevalence of structural neuroimaging abnormalities in our cohort with ONH/SOD was generally in the same range reported in other studies with corpus callosum abnormalities being relatively less common in our study. Bilateral NMD were relatively common among patients with NMD. The association between sex and ONH laterality requires further study.
Sections du résumé
BACKGROUND
BACKGROUND
Optic nerve hypoplasia (ONH) and septo-optic-pituitary dysplasia (SOD) are common causes of congenital visual impairment. Our primary aim was to investigate the prevalence of abnormal neuroimaging features in patients with these disorders in Manitoba, Canada, and compare them with published reports.
METHODS
METHODS
A retrospective neuroimaging review was performed in patients resident in Manitoba with ONH/SOD.
RESULTS
RESULTS
There were 128 patients (
CONCLUSION
CONCLUSIONS
The prevalence of structural neuroimaging abnormalities in our cohort with ONH/SOD was generally in the same range reported in other studies with corpus callosum abnormalities being relatively less common in our study. Bilateral NMD were relatively common among patients with NMD. The association between sex and ONH laterality requires further study.
Identifiants
pubmed: 37492885
pii: S0317167123002639
doi: 10.1017/cjn.2023.263
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM