The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease.
Journal
Arthritis & rheumatology (Hoboken, N.J.)
ISSN: 2326-5205
Titre abrégé: Arthritis Rheumatol
Pays: United States
ID NLM: 101623795
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
revised:
19
04
2023
received:
08
03
2023
accepted:
23
05
2023
medline:
29
9
2023
pubmed:
26
7
2023
entrez:
26
7
2023
Statut:
ppublish
Résumé
Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) and EULAR have developed the first-ever validated classification criteria for symptomatic CPPD disease. Supported by the ACR and EULAR, a multinational group of investigators followed established methodology to develop these disease classification criteria. The group generated lists of candidate items and refined their definitions, collected de-identified patient profiles, evaluated strengths of associations between candidate items and CPPD disease, developed a classification criteria framework, and used multi-criterion decision analysis to define criteria weights and a classification threshold score. The criteria were validated in an independent cohort. Among patients with joint pain, swelling, or tenderness (entry criterion) whose symptoms are not fully explained by an alternative disease (exclusion criterion), the presence of crowned dens syndrome or calcium pyrophosphate crystals in synovial fluid are sufficient to classify a patient as having CPPD disease. In the absence of these findings, a score >56 points using weighted criteria, comprising clinical features, associated metabolic disorders, and results of laboratory and imaging investigations, can be used to classify as CPPD disease. These criteria had a sensitivity of 92.2% and specificity of 87.9% in the derivation cohort (190 CPPD cases, 148 mimickers), whereas sensitivity was 99.2% and specificity was 92.5% in the validation cohort (251 CPPD cases, 162 mimickers). The 2023 ACR/EULAR CPPD disease classification criteria have excellent performance characteristics and will facilitate research in this field.
Identifiants
pubmed: 37494275
doi: 10.1002/art.42619
pmc: PMC10543651
mid: NIHMS1930282
doi:
Substances chimiques
Calcium Pyrophosphate
X69NU20D19
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1703-1713Subventions
Organisme : NIAMS NIH HHS
ID : K23 AR075070
Pays : United States
Organisme : NIAMS NIH HHS
ID : L30 AR070514
Pays : United States
Informations de copyright
© 2023 The Authors. Arthritis & Rheumatology published by Wiley Periodicals LLC on behalf of American College of Rheumatology.
Références
Osteoarthritis Cartilage. 2019 May;27(5):781-787
pubmed: 30738145
Ann Rheum Dis. 2018 Aug;77(8):1194-1199
pubmed: 29535120
Osteoarthritis Cartilage. 2021 May;29(5):619-632
pubmed: 33577959
Arthritis Care Res (Hoboken). 2022 Oct;74(10):1649-1658
pubmed: 33973414
Ann Rheum Dis. 2003 Jun;62(6):513-8
pubmed: 12759286
Clin Rheumatol. 2017 Mar;36(3):641-647
pubmed: 27837341
Ann Rheum Dis. 1957 Dec;16(4):494-502
pubmed: 13498604
Semin Arthritis Rheum. 2018 Aug;48(1):9-11
pubmed: 29338885
Arthritis Care Res (Hoboken). 2023 Apr;75(4):825-834
pubmed: 35439343
Clin Exp Rheumatol. 2009 Nov-Dec;27(6):981-4
pubmed: 20149316
Ann Rheum Dis. 2011 Apr;70(4):563-70
pubmed: 21216817
J Clin Epidemiol. 2014 Jun;67(6):706-14
pubmed: 24721558
Arthritis Rheumatol. 2021 Apr;73(4):687-692
pubmed: 33131218
RMD Open. 2022 Jun;8(2):
pubmed: 35701012
Clin Exp Rheumatol. 2016 Mar-Apr;34(2):254-60
pubmed: 26886247
Rheumatology (Oxford). 2023 Apr 3;62(4):1493-1500
pubmed: 35997554
Ann Rheum Dis. 2019 May;78(5):634-640
pubmed: 30692164
Ann Rheum Dis. 1999 May;58(5):261-3
pubmed: 10225806
J Rheumatol. 2017 Nov;44(11):1744-1749
pubmed: 28250136
Arthritis Rheumatol. 2015 Oct;67(10):2557-68
pubmed: 26352873
Arthritis Care Res (Hoboken). 2023 Mar;75(3):682-688
pubmed: 36426584
Clin Rheumatol. 2018 Oct;37(10):2847-2853
pubmed: 29882204
Clin Exp Rheumatol. 2005 Nov-Dec;23(6):819-28
pubmed: 16396700
J Rheumatol. 1989 Sep;16(9):1241-5
pubmed: 2810282
Ann Rheum Dis. 2019 Sep;78(9):1151-1159
pubmed: 31383717
J Clin Rheumatol. 2016 Oct;22(7):369-71
pubmed: 27660935
Clin Exp Rheumatol. 2020 Jan-Feb;38(1):99-106
pubmed: 31140401
Arthritis Rheum. 2010 Sep;62(9):2569-81
pubmed: 20872595
Arthritis Rheumatol. 2023 Apr;75(4):630-638
pubmed: 36122187
Rheumatology (Oxford). 2020 Apr 1;59(4):900-903
pubmed: 31630175