The risk of second primary cancer after nasopharyngeal cancer: a systematic review.
Head and neck cancer
Nasopharyngeal carcinoma
Second primary cancer
Systematic review
Journal
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
ISSN: 1434-4726
Titre abrégé: Eur Arch Otorhinolaryngol
Pays: Germany
ID NLM: 9002937
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
05
06
2023
accepted:
18
07
2023
medline:
2
1
2024
pubmed:
27
7
2023
entrez:
26
7
2023
Statut:
ppublish
Résumé
Second primary cancers (SPCs) after nasopharyngeal cancer (NPC) are rare, but have an impact on the follow-up of this patient population. The aim of this study is to systematically review the literature to determine the prevalence and most typical sites of SPCs after NPC. We searched the databases of PubMed, Web of Science, and Scopus for articles on SPCs after NPC. The Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines were followed. This review includes data on 89 168 patients with NPC from 21 articles. The mean occurrence for SPCs was 6.6% and varied from 4.9% in endemic areas to 8.7% in non-endemic areas. The most frequent locations of SPCs were oral cavity, pharynx, nose and paranasal sinuses, esophagus and lung. There is an increased risk for a SPC after NPC management, especially in non-endemic areas. However, their mean rate is lower than after other head and neck carcinomas.
Identifiants
pubmed: 37495725
doi: 10.1007/s00405-023-08144-0
pii: 10.1007/s00405-023-08144-0
pmc: PMC10562268
doi:
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
4775-4781Informations de copyright
© 2023. The Author(s).
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