Accelerometer-measured sedentary behavior and risk of functional disability in older Japanese adults: a 9-year prospective cohort study.
Accelerometry
Long-term care needs
Primary prevention
Risk factors
Sedentary time
Journal
The international journal of behavioral nutrition and physical activity
ISSN: 1479-5868
Titre abrégé: Int J Behav Nutr Phys Act
Pays: England
ID NLM: 101217089
Informations de publication
Date de publication:
26 07 2023
26 07 2023
Historique:
received:
23
02
2023
accepted:
06
07
2023
medline:
28
7
2023
pubmed:
27
7
2023
entrez:
26
7
2023
Statut:
epublish
Résumé
The associations of sedentary time and patterns with functional disability among older adults remain unclear, and few studies have accounted for the co-dependency of sedentary behavior and physical activities when modeling sedentary behavior with risk of functional disability. We aimed to examine the associations between sedentary time and patterns and risk of incident functional disability, and assess whether replacing sedentary time with light physical activity (LPA) or moderate-to-vigorous intensity physical activity (MVPA) is associated with reduced risk of functional disability in community-dwelling older adults. A total of 1,687 Japanese adults aged ≥ 65 years without functional disability at baseline were prospectively followed-up for 9 years (2011-2020). Functional disability was ascertained using the national database of Japan's Long-term Care Insurance System. Sedentary time and patterns, LPA, and MVPA were measured using a tri-axial accelerometer secured to participants' waists. During follow-up, 466 participants developed functional disability. Compared with the lowest quartile of total sedentary time, the multivariable-adjusted hazard ratios (95% confidence intervals) of functional disability for the second, third, and top quartiles were 1.21 (0.91‒1.62), 1.45 (1.10‒1.92), and 1.40 (1.05‒1.88) (p for trend = 0.01). After further adjusting for MVPA, total sedentary time was no longer significantly associated with the risk of functional disability (p for trend = 0.41). Replacing 10 min/day of sedentary time with the same amount of MVPA (but not LPA) was significantly associated with a 12% reduced risk of functional disability (hazard ratio [95% confidence interval]: 0.88 [0.84‒0.92]). No significant association was observed between sedentary bout length and functional disability. Higher levels of total sedentary time were associated with an increased risk of incident functional disability. However, this association was not independent of MVPA. Replacing sedentary time with MVPA, but not LPA, was associated with reduced risk of functional disability in older adults.
Sections du résumé
BACKGROUND
The associations of sedentary time and patterns with functional disability among older adults remain unclear, and few studies have accounted for the co-dependency of sedentary behavior and physical activities when modeling sedentary behavior with risk of functional disability. We aimed to examine the associations between sedentary time and patterns and risk of incident functional disability, and assess whether replacing sedentary time with light physical activity (LPA) or moderate-to-vigorous intensity physical activity (MVPA) is associated with reduced risk of functional disability in community-dwelling older adults.
METHODS
A total of 1,687 Japanese adults aged ≥ 65 years without functional disability at baseline were prospectively followed-up for 9 years (2011-2020). Functional disability was ascertained using the national database of Japan's Long-term Care Insurance System. Sedentary time and patterns, LPA, and MVPA were measured using a tri-axial accelerometer secured to participants' waists.
RESULTS
During follow-up, 466 participants developed functional disability. Compared with the lowest quartile of total sedentary time, the multivariable-adjusted hazard ratios (95% confidence intervals) of functional disability for the second, third, and top quartiles were 1.21 (0.91‒1.62), 1.45 (1.10‒1.92), and 1.40 (1.05‒1.88) (p for trend = 0.01). After further adjusting for MVPA, total sedentary time was no longer significantly associated with the risk of functional disability (p for trend = 0.41). Replacing 10 min/day of sedentary time with the same amount of MVPA (but not LPA) was significantly associated with a 12% reduced risk of functional disability (hazard ratio [95% confidence interval]: 0.88 [0.84‒0.92]). No significant association was observed between sedentary bout length and functional disability.
CONCLUSION
Higher levels of total sedentary time were associated with an increased risk of incident functional disability. However, this association was not independent of MVPA. Replacing sedentary time with MVPA, but not LPA, was associated with reduced risk of functional disability in older adults.
Identifiants
pubmed: 37496006
doi: 10.1186/s12966-023-01490-6
pii: 10.1186/s12966-023-01490-6
pmc: PMC10369703
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
91Informations de copyright
© 2023. The Author(s).
Références
JAMA Oncol. 2020 Aug 1;6(8):1210-1217
pubmed: 32556069
Gait Posture. 2010 Mar;31(3):370-4
pubmed: 20138524
J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1525-1531
pubmed: 29165626
Int J Behav Nutr Phys Act. 2010 May 11;7:38
pubmed: 20459782
Med Sci Sports Exerc. 2005 Nov;37(11 Suppl):S531-43
pubmed: 16294116
Phys Ther. 2022 May 5;102(5):
pubmed: 35079837
J Am Geriatr Soc. 2021 Mar;69(3):718-725
pubmed: 33252141
BMJ Open Sport Exerc Med. 2019 Oct 28;5(1):e000592
pubmed: 31749982
J Am Geriatr Soc. 2005 Mar;53(3):522-7
pubmed: 15743300
Stat Med. 1989 May;8(5):551-61
pubmed: 2657958
J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):188-198
pubmed: 30920779
Am J Prev Med. 2018 Sep;55(3):395-402
pubmed: 30122216
Clin Interv Aging. 2021 Oct 28;16:1877-1915
pubmed: 34737555
BMC Public Health. 2016 Aug 26;16:888
pubmed: 27562190
J Gerontol A Biol Sci Med Sci. 2013 Dec;68(12):1518-24
pubmed: 23682162
J Gerontol A Biol Sci Med Sci. 2018 Mar 14;73(4):532-538
pubmed: 28958064
Br J Nutr. 2011 Jun;105(11):1681-91
pubmed: 21262061
Neuroepidemiology. 2013;40(1):23-9
pubmed: 23075757
Diabetes Care. 2021 Feb;44(2):563-570
pubmed: 33273043
Arch Gerontol Geriatr. 2013 Sep-Oct;57(2):177-83
pubmed: 23684243
J Am Heart Assoc. 2021 Feb 2;10(3):e018350
pubmed: 33470140
Ann Intern Med. 2015 Jan 20;162(2):123-32
pubmed: 25599350
J Intern Med. 2009 Feb;265(2):288-95
pubmed: 19192038
BMC Geriatr. 2015 Apr 02;15:36
pubmed: 25887474
Lancet. 2016 Sep 24;388(10051):1302-10
pubmed: 27475271
Geriatr Gerontol Int. 2015 Apr;15(4):518-9
pubmed: 25828791
Br J Sports Med. 2020 Dec;54(24):1499-1506
pubmed: 33239356
BMJ. 2014 Apr 29;348:g2472
pubmed: 24782514
Circulation. 2019 Feb 19;139(8):1036-1046
pubmed: 31031411
J Nutr Health Aging. 2019;23(9):856-861
pubmed: 31641736
Br J Sports Med. 2020 Dec;54(24):1451-1462
pubmed: 33239350
Int J Geriatr Psychiatry. 2003 Apr;18(4):346-52
pubmed: 12673612
Scand J Med Sci Sports. 2021 Jan;31(1):153-162
pubmed: 32945566
J Gerontol A Biol Sci Med Sci. 2020 Sep 16;75(9):1763-1770
pubmed: 32134454
J Gerontol A Biol Sci Med Sci. 2014 Jul;69(7):843-51
pubmed: 24270063
Geriatr Gerontol Int. 2012 Apr;12(2):310-6
pubmed: 22122408
Int J Behav Nutr Phys Act. 2021 Jul 12;18(1):83
pubmed: 34247647
Ann Intern Med. 2017 Oct 03;167(7):465-475
pubmed: 28892811
Ageing Res Rev. 2021 May;67:101266
pubmed: 33607291
Am J Clin Nutr. 1997 Apr;65(4 Suppl):1220S-1228S; discussion 1229S-1231S
pubmed: 9094926
Am J Epidemiol. 2009 Aug 15;170(4):519-27
pubmed: 19584129
Am J Public Health. 1994 Aug;84(8):1274-80
pubmed: 8059885
J Am Geriatr Soc. 2016 Dec;64(12):2495-2502
pubmed: 27801931
Geriatr Gerontol Int. 2016 Jun;16(6):709-15
pubmed: 26171645
Am J Epidemiol. 1986 Jul;124(1):17-27
pubmed: 3521261