Application of AllerCatPro 2.0 for protein safety assessments of consumer products.
IgE antibody
bioinformatics
botanicals
in silico
natural substances
protein allergenicity
risk assessment
Journal
Frontiers in allergy
ISSN: 2673-6101
Titre abrégé: Front Allergy
Pays: Switzerland
ID NLM: 9918227355906676
Informations de publication
Date de publication:
2023
2023
Historique:
received:
20
04
2023
accepted:
27
06
2023
medline:
27
7
2023
pubmed:
27
7
2023
entrez:
27
7
2023
Statut:
epublish
Résumé
Foreign proteins are potentially immunogenic, and a proportion of these are able to induce immune responses that result in allergic sensitization. Subsequent exposure of sensitized subjects to the inducing protein can provoke a variety of allergic reactions that may be severe, or even fatal. It has therefore been recognized for some time that it is important to determine
Identifiants
pubmed: 37497076
doi: 10.3389/falgy.2023.1209495
pmc: PMC10367106
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1209495Informations de copyright
© 2023 Krutz, Kimber, Winget, Nguyen, Limviphuvadh, Maurer-Stroh, Mahony and Gerberick.
Déclaration de conflit d'intérêts
Authors GG, sole proprietor of GF3 Consultancy LLC, and IK received financial compensation from P&G for their time spent in the preparation of this publication. This article was prepared during the normal course of the authors’ affiliations or employment shown on the first page of the paper. NK, JW, and CM are current employees of P&G that develops and sells consumer products and provided financial support for this research. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. None of these authors has participated in legal or regulatory proceedings on the subject of this paper during the last 5 years. The authors have sole responsibility for the preparation and content of this manuscript.
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