Preeclampsia and risk of maternal pulmonary hypertension at high altitude in Bolivia.

COPD Chronic hypoxia HAPE gestational hypertension high altitude hypertensive disorders of pregnancy maternal mortality pulmonary hypertension

Journal

Journal of developmental origins of health and disease
ISSN: 2040-1752
Titre abrégé: J Dev Orig Health Dis
Pays: England
ID NLM: 101517692

Informations de publication

Date de publication:
08 2023
Historique:
medline: 23 10 2023
pubmed: 27 7 2023
entrez: 27 7 2023
Statut: ppublish

Résumé

Women with a history of preeclampsia (PE) have a greater risk of pulmonary arterial hypertension (PAH). In turn, pregnancy at high altitude is a risk factor for PE. However, whether women who develop PE during highland pregnancy are at risk of PAH before and after birth has not been investigated. We tested the hypothesis that during highland pregnancy, women who develop PE are at greater risk of PAH compared to women undergoing healthy highland pregnancies. The study was on 140 women in La Paz, Bolivia (3640m). Women undergoing healthy highland pregnancy were controls (C,

Identifiants

pubmed: 37497575
pii: S2040174423000193
doi: 10.1017/S2040174423000193
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

523-531

Subventions

Organisme : British Heart Foundation
ID : FS/02/072/13469
Pays : United Kingdom
Organisme : British Heart Foundation
ID : RG/06/006/22028
Pays : United Kingdom

Auteurs

C E Salinas (CE)

Instituto Boliviano de Biología de Altura (IBBA), UMSA, La Paz, Bolivia.

O V Patey (OV)

Department of Physiology, Development & Neuroscience, University of Cambridge, Cambridge, UK.

C Murillo (C)

Instituto Boliviano de Biología de Altura (IBBA), UMSA, La Paz, Bolivia.

M Gonzales (M)

Instituto Boliviano de Biología de Altura (IBBA), UMSA, La Paz, Bolivia.

V Espinoza (V)

Instituto Boliviano de Biología de Altura (IBBA), UMSA, La Paz, Bolivia.

S Mendoza (S)

Centro de Salud Tembladerani, La Paz, Bolivia.

R Ruiz (R)

Hospital Materno Infantil, La Paz, Bolivia.

R Vargas (R)

Hospital de la Mujer, La Paz, Bolivia.

Y Perez (Y)

Hospital de la Mujer, La Paz, Bolivia.

J Montaño (J)

Hospital de la Mujer, La Paz, Bolivia.

L Toledo-Jaldin (L)

Hospital Materno Infantil, La Paz, Bolivia.

A Badner (A)

Hospital Materno Infantil, La Paz, Bolivia.

J Jimenez (J)

Instituto Boliviano de Biología de Altura (IBBA), UMSA, La Paz, Bolivia.

J Peñaranda (J)

Facultad de Medicina, UMSA, La Paz, Bolivia.

C Romero (C)

Instituto Boliviano de Biología de Altura (IBBA), UMSA, La Paz, Bolivia.

M Aguilar (M)

Instituto Boliviano de Biología de Altura (IBBA), UMSA, La Paz, Bolivia.

L Riveros (L)

Instituto Boliviano de Biología de Altura (IBBA), UMSA, La Paz, Bolivia.

I Arana (I)

Grupo Premio Nobel, La Paz, Bolivia.

D A Giussani (DA)

Department of Physiology, Development & Neuroscience, University of Cambridge, Cambridge, UK.
BHF Centre for Research Excellence, University of Cambridge, Cambridge, UK.
Strategic Research Initiative in Reproduction, University of Cambridge, Cambridge, UK.

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Classifications MeSH