A high-throughput 3D kinetic killing assay.
3D matrix
cytotoxicity assay
high content imaging
high throughput
translational immunology
Journal
European journal of immunology
ISSN: 1521-4141
Titre abrégé: Eur J Immunol
Pays: Germany
ID NLM: 1273201
Informations de publication
Date de publication:
11 2023
11 2023
Historique:
revised:
24
07
2023
received:
27
03
2023
accepted:
26
07
2023
medline:
2
11
2023
pubmed:
28
7
2023
entrez:
28
7
2023
Statut:
ppublish
Résumé
Our work presents a high-throughput kinetic killing assay in the 3D matrix using high-content imaging that is a robust and powerful cytotoxicity assay for evaluating the killing efficiency of immune killer cells or conducting drug screening under physiologically and pathologically relevant scenarios, particularly in the context of solid tumors.
Identifiants
pubmed: 37501396
doi: 10.1002/eji.202350505
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2350505Informations de copyright
© 2023 The Authors. European Journal of Immunology published by Wiley-VCH GmbH.
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