Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis.

DOAC anticoagulation apixaban embolic stroke heparin non-bacterial thrombotic endocarditis warfarin

Journal

Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388

Informations de publication

Date de publication:
2023
Historique:
received: 18 04 2023
accepted: 26 06 2023
medline: 28 7 2023
pubmed: 28 7 2023
entrez: 28 7 2023
Statut: epublish

Résumé

An elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch the patient to LMWH for anticoagulation was then made and a follow-up TEE showed resolution of the NBTE. In this abstract, we show that heparin should remain as the anticoagulation agent of choice in the setting of NBTE associated with malignancy.

Identifiants

pubmed: 37502185
doi: 10.3389/fcvm.2023.1208190
pmc: PMC10369060
doi:

Types de publication

Case Reports

Langues

eng

Pagination

1208190

Informations de copyright

© 2023 Akiki, Ahmad, El-Am, Casanegra, Klarich and Kurmann.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Elias Akiki (E)

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.

Ali Ahmad (A)

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.
Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United States.

Edward A El-Am (EA)

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.

Ana I Casanegra (AI)

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.

Kyle W Klarich (KW)

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.

Reto Kurmann (R)

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.

Classifications MeSH