Glycolipids from the gut symbiont


Journal

Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951

Informations de publication

Date de publication:
26 Jul 2023
Historique:
received: 25 04 2023
accepted: 26 05 2023
medline: 28 7 2023
pubmed: 28 7 2023
entrez: 28 7 2023
Statut: epublish

Résumé

Natural Killer T (NKT) cells are a lipid-antigen reactive T cell subset that is restricted to the antigen presenting molecule CD1d. They possess diverse functional properties that contribute to inflammatory and regulatory immune responses. The most studied lipid antigen target for these T cells is α-galactosylceramide (αGC). The commensal organism

Identifiants

pubmed: 37502334
doi: 10.1039/d3sc02124f
pii: d3sc02124f
pmc: PMC10370605
doi:

Types de publication

Journal Article

Langues

eng

Pagination

7887-7896

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

D. I. G. is a member of the scientific advisory board for Avalia Immunotherapies, a company that is developing natural killer T cell-based vaccines.

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Auteurs

Garth Cameron (G)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne VIC 3000 Australia godfrey@unimelb.edu.au.

Tram Nguyen (T)

School of Chemistry, University of Melbourne Parkville VIC 3010 Australia sjwill@unimelb.edu.au.
Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville VIC 3010 Australia.

Marcin Ciula (M)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne VIC 3000 Australia godfrey@unimelb.edu.au.

Spencer J Williams (SJ)

School of Chemistry, University of Melbourne Parkville VIC 3010 Australia sjwill@unimelb.edu.au.
Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville VIC 3010 Australia.

Dale I Godfrey (DI)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne Melbourne VIC 3000 Australia godfrey@unimelb.edu.au.

Classifications MeSH