A Cell Cycle-Dependent Ferroptosis Sensitivity Switch Governed by EMP2.

EMP2 Lipid peroxidation MBOAT1 MUFA PUFA ferroptosis p53

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
19 Jul 2023
Historique:
pubmed: 28 7 2023
medline: 28 7 2023
entrez: 28 7 2023
Statut: epublish

Résumé

Ferroptosis is a non-apoptotic form of cell death characterized by iron-dependent lipid peroxidation. Ferroptosis can be induced by system x

Identifiants

DOI: 10.1101/2023.07.19.549715 PMID: 37502927 PMC: PMC10370086
pubmed: 37502927
doi: 10.1101/2023.07.19.549715
pmc: PMC10370086
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NCI NIH HHS
ID : F31 CA265146
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA262439
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM112948
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM122923
Pays : United States

Déclaration de conflit d'intérêts

DECLARATION OF INTERESTS S.J.D. is a founder of Prothegen Inc., a member of the scientific advisory board of Ferro Therapeutics and Hillstream Biopharma, and an inventor on patents related to ferroptosis.

Auteurs

Jason Rodencal (J)

Department of Biology, Stanford University, Stanford, CA 94305, USA.

Nathan Kim (N)

Department of Biology, Stanford University, Stanford, CA 94305, USA.

Veronica L Li (VL)

Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Andrew He (A)

Departments of Pediatrics and Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

Mike Lange (M)

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA.

Jianping He (J)

Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.

Amy Tarangelo (A)

Department of Biology, Stanford University, Stanford, CA 94305, USA.

Zachary T Schafer (ZT)

Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.

James A Olzmann (JA)

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA.
Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.

Julien Sage (J)

Departments of Pediatrics and Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

Jonathan Z Long (JZ)

Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Scott J Dixon (SJ)

Department of Biology, Stanford University, Stanford, CA 94305, USA.
Lead contact.

Classifications MeSH