Structure of HK97 small terminase:DNA complex unveils a novel DNA binding mechanism by a circular protein.

HK97 small terminase bacteriophage cryoEM structure protein:DNA complex

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
20 Jul 2023
Historique:
pubmed: 28 7 2023
medline: 28 7 2023
entrez: 28 7 2023
Statut: epublish

Résumé

DNA recognition is critical for assembly of double-stranded DNA viruses, in particular for the initiation of packaging the viral genome into the capsid. DNA packaging has been extensively studied for three archetypal bacteriophage systems:

Identifiants

pubmed: 37503206
doi: 10.1101/2023.07.17.549218
pmc: PMC10370121
pii:
doi:

Types de publication

Preprint

Langues

eng

Déclaration de conflit d'intérêts

Competing interests The authors declare no competing interests.

Auteurs

Maria Chechik (M)

York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.

Sandra J Greive (SJ)

York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.

Alfred A Antson (AA)

York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.

Huw T Jenkins (HT)

York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.

Classifications MeSH