Beraprost and Overall Survival in Cats with Chronic Kidney Disease.
beraprost
chronic kidney disease
feline
overall survival
progression-free survival
Journal
Veterinary sciences
ISSN: 2306-7381
Titre abrégé: Vet Sci
Pays: Switzerland
ID NLM: 101680127
Informations de publication
Date de publication:
13 Jul 2023
13 Jul 2023
Historique:
received:
11
05
2023
revised:
07
07
2023
accepted:
11
07
2023
medline:
28
7
2023
pubmed:
28
7
2023
entrez:
28
7
2023
Statut:
epublish
Résumé
Overall survival is the most important outcome for treatment response in feline chronic kidney disease (CKD). Beraprost has been shown to reduce the kidney function decline in cats with International Renal Interest Society (IRIS) stage 2 and 3 CKD. However, the association with prolonged survival has not yet been examined. To assess the relationship between beraprost and overall survival in cats with CKD in real clinical practice. Client-owned cats with IRIS stage 3 CKD ( A retrospective cohort study based on data from electronic medical records of one hospital. The cohort was divided into "beraprost therapy" and "no beraprost therapy" groups, and survival analyses revealed that overall survival was significantly longer in the beraprost therapy group, using Kaplan-Meier curves ( In feline patients with CKD, beraprost therapy is associated with better overall survival.
Sections du résumé
BACKGROUND
BACKGROUND
Overall survival is the most important outcome for treatment response in feline chronic kidney disease (CKD). Beraprost has been shown to reduce the kidney function decline in cats with International Renal Interest Society (IRIS) stage 2 and 3 CKD. However, the association with prolonged survival has not yet been examined.
OBJECTIVE
OBJECTIVE
To assess the relationship between beraprost and overall survival in cats with CKD in real clinical practice.
ANIMALS
METHODS
Client-owned cats with IRIS stage 3 CKD (
METHODS
METHODS
A retrospective cohort study based on data from electronic medical records of one hospital.
RESULTS
RESULTS
The cohort was divided into "beraprost therapy" and "no beraprost therapy" groups, and survival analyses revealed that overall survival was significantly longer in the beraprost therapy group, using Kaplan-Meier curves (
CONCLUSIONS
CONCLUSIONS
In feline patients with CKD, beraprost therapy is associated with better overall survival.
Identifiants
pubmed: 37505864
pii: vetsci10070459
doi: 10.3390/vetsci10070459
pmc: PMC10384921
pii:
doi:
Types de publication
Journal Article
Langues
eng
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