Population norms for the EQ-5D-3L and EQ-5D-5L in Romania.


Journal

Health and quality of life outcomes
ISSN: 1477-7525
Titre abrégé: Health Qual Life Outcomes
Pays: England
ID NLM: 101153626

Informations de publication

Date de publication:
29 Jul 2023
Historique:
received: 08 10 2022
accepted: 05 06 2023
medline: 31 7 2023
pubmed: 29 7 2023
entrez: 28 7 2023
Statut: epublish

Résumé

The majority of patient reported outcome measures (PROMs) don't have population norms in Romania. This is the case with the EQ-5D as well. Therefore, we aimed to estimate population norms for the Romanian versions of the EQ-5D-5L, EQ-5D-3L, their indexes, and the EQ-VAS. A cross-sectional survey was conducted in all regions of Romania from November 2018 to November 2019. A three-stage probability sampling procedure stratified by region and settlement size was used to select a representative sample. Interviews were computer-assisted and conducted in respondents' homes by trained interviewers. Health status was assessed with the EQ-5D-5L, the EQ-5D-3L and the EQ VAS. Descriptive statistics were used to estimate population norms by age groups and sex for the EQ-5D-5L, the EQ-5D-3L, their indexes and the EQ VAS. Population norms were weighted using survey weights. Indexes for the EQ-5D questionnaires were estimated using the recently developed Romanian value sets. Data from 1,649 interviews was analysed in the present study. Survey weights were used so that sex and place of residence ratios for the weighted sample matched the Romanian general population distribution. Participants' mean age was 47.4 years (SE = 1.157) and 50.3% of them reported being in good health. The dimension for which people reported the highest number of problems for both questionnaires was the pain/discomfort dimension. Men aged 35 plus reported fewer problems with pain/discomfort than women for both the EQ-5D-5L and EQ-5D-3L. Health decreased with age as shown by the decrease from age group 18-24 to age group 75 plus in the indexes of both questionnaires: from 0.977 (SE = 0.005) to 0.765 (SE = 0.017) for EQ-5D-5L and from 0.981 (SE = 0.005) to 0.784 (SE = 0.019) for EQ-5D-3L. There was 29.9 points drop in the EQ VAS score between the youngest and oldest group. Population norms for the Romanian versions of the EQ-5D-5L, EQ-5D-3L, their indexes, and the EQ VAS are now available. These can now be used as reference values by healthcare professionals, researchers and decision-makers leading to a further development of health-related quality of life research in Romania.

Sections du résumé

BACKGROUND BACKGROUND
The majority of patient reported outcome measures (PROMs) don't have population norms in Romania. This is the case with the EQ-5D as well. Therefore, we aimed to estimate population norms for the Romanian versions of the EQ-5D-5L, EQ-5D-3L, their indexes, and the EQ-VAS.
METHODS METHODS
A cross-sectional survey was conducted in all regions of Romania from November 2018 to November 2019. A three-stage probability sampling procedure stratified by region and settlement size was used to select a representative sample. Interviews were computer-assisted and conducted in respondents' homes by trained interviewers. Health status was assessed with the EQ-5D-5L, the EQ-5D-3L and the EQ VAS. Descriptive statistics were used to estimate population norms by age groups and sex for the EQ-5D-5L, the EQ-5D-3L, their indexes and the EQ VAS. Population norms were weighted using survey weights. Indexes for the EQ-5D questionnaires were estimated using the recently developed Romanian value sets.
RESULTS RESULTS
Data from 1,649 interviews was analysed in the present study. Survey weights were used so that sex and place of residence ratios for the weighted sample matched the Romanian general population distribution. Participants' mean age was 47.4 years (SE = 1.157) and 50.3% of them reported being in good health. The dimension for which people reported the highest number of problems for both questionnaires was the pain/discomfort dimension. Men aged 35 plus reported fewer problems with pain/discomfort than women for both the EQ-5D-5L and EQ-5D-3L. Health decreased with age as shown by the decrease from age group 18-24 to age group 75 plus in the indexes of both questionnaires: from 0.977 (SE = 0.005) to 0.765 (SE = 0.017) for EQ-5D-5L and from 0.981 (SE = 0.005) to 0.784 (SE = 0.019) for EQ-5D-3L. There was 29.9 points drop in the EQ VAS score between the youngest and oldest group.
CONCLUSIONS CONCLUSIONS
Population norms for the Romanian versions of the EQ-5D-5L, EQ-5D-3L, their indexes, and the EQ VAS are now available. These can now be used as reference values by healthcare professionals, researchers and decision-makers leading to a further development of health-related quality of life research in Romania.

Identifiants

pubmed: 37507760
doi: 10.1186/s12955-023-02144-8
pii: 10.1186/s12955-023-02144-8
pmc: PMC10386277
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

80

Subventions

Organisme : H2020 Marie Skłodowska-Curie Actions
ID : 748612
Organisme : H2020 Marie Skłodowska-Curie Actions
ID : 748612
Organisme : H2020 Marie Skłodowska-Curie Actions
ID : 748612
Organisme : EuroQol Research Foundation
ID : 20180030R1
Organisme : EuroQol Research Foundation
ID : 20180030R1
Organisme : EuroQol Research Foundation
ID : 20180030R1
Organisme : Romanian Operational Programme "Administrative Capacity"
ID : SIPOCA Code 195/MySMIS 111603

Informations de copyright

© 2023. The Author(s).

Références

Patient. 2020 Aug;13(4):435-443
pubmed: 32346816
Arch Med Sci. 2017 Feb 1;13(1):191-200
pubmed: 28144271
Value Health Reg Issues. 2020 Sep;22:93-98
pubmed: 32823061
Qual Life Res. 2016 Nov;25(11):2693-2710
pubmed: 27472992
Qual Life Res. 2006 Dec;15(10):1651-61
pubmed: 17031501
Popul Health Metr. 2018 Aug 16;16(1):14
pubmed: 30115092
Pharmacoeconomics. 2000 Jan;17(1):13-35
pubmed: 10747763
Health Qual Life Outcomes. 2015 Nov 26;13:191
pubmed: 26612336
Pharmacoeconomics. 2018 Jun;36(6):645-661
pubmed: 29572719
Appl Health Econ Health Policy. 2017 Apr;15(2):127-137
pubmed: 28194657
Med Decis Making. 1997 Apr-Jun;17(2):208-16
pubmed: 9107617
BMC Med. 2011 Jul 14;9:86
pubmed: 21756344
Qual Life Res. 2021 Mar;30(3):831-840
pubmed: 33237551
Int J Environ Res Public Health. 2021 Jul 11;18(14):
pubmed: 34299864
Health Qual Life Outcomes. 2020 Oct 7;18(1):333
pubmed: 33028345
Soz Praventivmed. 2002;47(4):203-4
pubmed: 12415920
Qual Life Res. 2022 Feb;31(2):517-526
pubmed: 34272631
Eur J Health Econ. 2023 Apr;24(3):399-412
pubmed: 35688994
Med Care. 1983 Feb;21(2):193-207
pubmed: 6827873
Value Health. 2020 Sep;23(9):1235-1245
pubmed: 32940242
Pol Arch Med Wewn. 2015;125(1-2):18-26
pubmed: 25578383
Patient Relat Outcome Meas. 2019 Jul 29;10:233-241
pubmed: 31534379
Med Decis Making. 2018 Nov;38(8):968-982
pubmed: 30403577
Eur J Health Econ. 2014 May;15 Suppl 1:S13-25
pubmed: 24832832
Health Qual Life Outcomes. 2010 Dec 02;8:146
pubmed: 21126374
Eur J Health Econ. 2020 Nov;21(8):1169-1178
pubmed: 32813084
Health Policy. 2008 Mar;85(3):263-76
pubmed: 17931736
HRB Open Res. 2018 Sep 4;1:22
pubmed: 32002510
Orv Hetil. 2003 Aug 24;144(34):1667-74
pubmed: 14528840
Value Health. 2008 Mar-Apr;11(2):275-84
pubmed: 18380640
BMJ Open. 2019 Aug 18;9(8):e029067
pubmed: 31427330
Econ Hum Biol. 2019 Dec;35:207-221
pubmed: 31671367

Auteurs

Elena Olariu (E)

Health Economics Group, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK. elena.olariu@newcastle.ac.uk.

Raluca Caplescu (R)

Department of Statistics and Econometrics, Bucharest University of Economic Studies, Bucharest, 010374, Romania.

Luke Vale (L)

Health Economics Group, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

Ileana Gabriela Niculescu-Aron (IG)

Department of Statistics and Econometrics, Bucharest University of Economic Studies, Bucharest, 010374, Romania.

Yemi Oluboyede (Y)

Health Economics Group, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.

Marian Sorin Paveliu (MS)

Department of Pharmacology, Titu Maiorescu University, Bucharest, 031593, Romania.
Romanian Academic Society, Bucharest, 020071, Romania.

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Classifications MeSH