Discovery of Bactericidal Proteins from

Hypothetical Proteins of Unknown Function (HPUFs) Staphylococcus aureus antimicrobial resistance bacteriophages cross-species toxicity

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
21 Jul 2023
Historique:
received: 27 06 2023
revised: 11 07 2023
accepted: 19 07 2023
medline: 29 7 2023
pubmed: 29 7 2023
entrez: 29 7 2023
Statut: epublish

Résumé

In the escalating battle against antimicrobial resistance, there is an urgent need to discover and investigate new antibiotic strategies. Bacteriophages are untapped reservoirs of such potential antimicrobials. This study focused on Hypothetical Proteins of Unknown Function (HPUFs) from a

Identifiants

pubmed: 37508310
pii: antibiotics12071213
doi: 10.3390/antibiotics12071213
pmc: PMC10376165
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Academy of Finland
ID : 288701
Organisme : Jane and Aatos Erkko Foundation
ID : 200050
Organisme : Jane and Aatos Erkko Foundation
ID : Decision 2016

Références

PLoS One. 2021 Feb 10;16(2):e0246918
pubmed: 33566854
PLoS One. 2015 Dec 21;10(12):e0144710
pubmed: 26690351
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W244-8
pubmed: 15980461
Nucleic Acids Res. 1993 Sep 11;21(18):4411-2
pubmed: 8415012
J Bacteriol. 2022 Sep 20;204(9):e0023022
pubmed: 35916528
Microbiology (Reading). 2019 Jul;165(7):722-736
pubmed: 31091188
Curr Opin Biotechnol. 2021 Apr;68:1-7
pubmed: 33007632
Front Microbiol. 2019 Apr 01;10:539
pubmed: 30988669
Nat Methods. 2005 Jun;2(6):443-8
pubmed: 15908923
J Bacteriol. 2015 Jan 1;197(1):7-17
pubmed: 25157079
Eur J Biochem. 1992 Mar 15;204(3):1149-54
pubmed: 1551392
Future Microbiol. 2012 Oct;7(10):1147-71
pubmed: 23030422
Nat Biotechnol. 2004 Feb;22(2):185-91
pubmed: 14716317
Viruses. 2020 Jan 23;12(2):
pubmed: 31979276
J Glob Infect Dis. 2010 Sep;2(3):275-83
pubmed: 20927290
Arch Microbiol. 1994;161(3):199-206
pubmed: 8161282
J Mol Biol. 2018 Jul 20;430(15):2237-2243
pubmed: 29258817
Nat Protoc. 2015 Jun;10(6):845-58
pubmed: 25950237
Nucleic Acids Res. 2020 Sep 4;48(15):8545-8561
pubmed: 32735661
Bacteriophage. 2015 Jun 23;5(3):e1062590
pubmed: 26442196
Arch Virol. 2019 Aug;164(8):2171-2173
pubmed: 31093759
Nucleic Acids Res. 2008 Apr;36(6):2094-105
pubmed: 18281701
EMBO J. 1986 Apr;5(4):823-6
pubmed: 3709526
Br J Pharmacol. 2011 May;163(1):184-94
pubmed: 21323894
Nature. 2021 Aug;596(7873):583-589
pubmed: 34265844
Viruses. 2021 Apr 24;13(5):
pubmed: 33923360
Plasmid. 2009 Mar;61(2):126-9
pubmed: 18996145
Pathog Glob Health. 2015;109(7):309-18
pubmed: 26343252
Bacteriophage. 2013 Apr 1;3(2):e25518
pubmed: 24228223
Microbiology (Reading). 2011 Dec;157(Pt 12):3314-3323
pubmed: 21921101
J Bacteriol. 1995 Jul;177(14):4121-30
pubmed: 7608087

Auteurs

Ellisiv Nyhamar (E)

Department of Bacteriology and Immunology, Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Department of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, 00790 Helsinki, Finland.

Paige Webber (P)

Department of Bacteriology and Immunology, Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.

Olivia Liong (O)

Department of Bacteriology and Immunology, Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.

Özgenur Yilmaz (Ö)

Department of Bacteriology and Immunology, Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Faculty of Health Sciences, Kirklareli University, 39000 Kirklareli, Turkey.

Maria Pajunen (M)

Department of Bacteriology and Immunology, Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.

Mikael Skurnik (M)

Department of Bacteriology and Immunology, Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.

Xing Wan (X)

Department of Bacteriology and Immunology, Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Department of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, 00790 Helsinki, Finland.

Classifications MeSH