The

HPV TP53 head and neck cancer singe-nucleotide polymorphism somatic mutation

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
26 Jun 2023
Historique:
received: 22 05 2023
revised: 19 06 2023
accepted: 24 06 2023
medline: 29 7 2023
pubmed: 29 7 2023
entrez: 29 7 2023
Statut: epublish

Résumé

Somatic To study Using a custom-made next-generation sequencing (NGS) panel on formalin-fixed, paraffin-embedded tumor tissue, we analyzed somatic Only 2 of 44 patients with HPV-positive (HPV(+)) HNSCC had a Our observations show that

Sections du résumé

BACKGROUND BACKGROUND
Somatic
OBJECTIVE OBJECTIVE
To study
METHODS METHODS
Using a custom-made next-generation sequencing (NGS) panel on formalin-fixed, paraffin-embedded tumor tissue, we analyzed somatic
RESULTS RESULTS
Only 2 of 44 patients with HPV-positive (HPV(+)) HNSCC had a
CONCLUSIONS CONCLUSIONS
Our observations show that

Identifiants

pubmed: 37509476
pii: biomedicines11071838
doi: 10.3390/biomedicines11071838
pmc: PMC10376802
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Western Norway Regional Health Authority
ID : F-12125

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Auteurs

Svein Erik Moe (SE)

Department of Otolaryngology/Head and Neck Surgery, Haukeland University Hospital (HUS), N-5020 Bergen, Norway.

Fredrik A Erland (FA)

Department of Otolaryngology/Head and Neck Surgery, Haukeland University Hospital (HUS), N-5020 Bergen, Norway.

Siren Fromreide (S)

Department of Clinical Medicine, University of Bergen, N-5020 Bergen, Norway.

Stein Lybak (S)

Department of Otolaryngology/Head and Neck Surgery, Haukeland University Hospital (HUS), N-5020 Bergen, Norway.

Marianne Brydoy (M)

Department of Oncology, Haukeland University Hospital (HUS), N-5020 Bergen, Norway.

Harsh N Dongre (HN)

Department of Clinical Medicine, University of Bergen, N-5020 Bergen, Norway.

Sophia M Dhayalan (SM)

Department of Pathology, Haukeland University Hospital (HUS), N-5020 Bergen, Norway.

Daniela-Elena Costea (DE)

Department of Clinical Medicine, University of Bergen, N-5020 Bergen, Norway.

Olav K Vintermyr (OK)

Department of Pathology, Haukeland University Hospital (HUS), N-5020 Bergen, Norway.

Hans Jørgen Aarstad (HJ)

Department of Clinical Medicine, University of Bergen, N-5020 Bergen, Norway.

Classifications MeSH