Platelet Adhesion Mediated by von Willebrand Factor at High Shear Rates Is Associated with Premature Coronary Artery Disease.

GPIb coronary artery disease platelet adhesion von Willebrand factor

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
06 Jul 2023
Historique:
received: 16 06 2023
revised: 04 07 2023
accepted: 05 07 2023
medline: 29 7 2023
pubmed: 29 7 2023
entrez: 29 7 2023
Statut: epublish

Résumé

This study investigated von Willebrand factor (VWF)-mediated platelet adhesion at high shear rates in patients with premature coronary artery disease (CAD). The study included 84 patients with stable premature CAD and 64 patients without CAD. Whole blood samples were perfused through a microfluidic cell over a collagen-coated surface at a shear rate of 1300 s

Identifiants

pubmed: 37509554
pii: biomedicines11071916
doi: 10.3390/biomedicines11071916
pmc: PMC10377430
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Russian Science Foundation
ID : 21-15-00029

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Auteurs

Sergey Okhota (S)

Department of Problems of Atherosclerosis, National Medical Research Centre of Cardiology Named after Academician E.I. Chazov of the Ministry of Health of the Russian Federation, 121552 Moscow, Russia.

Sergey Kozlov (S)

Department of Problems of Atherosclerosis, National Medical Research Centre of Cardiology Named after Academician E.I. Chazov of the Ministry of Health of the Russian Federation, 121552 Moscow, Russia.

Yuliya Avtaeva (Y)

Laboratory of Cell Hemostasis, National Medical Research Centre of Cardiology Named after Academician E.I. Chazov of the Ministry of Health of the Russian Federation, 121552 Moscow, Russia.

Ivan Melnikov (I)

Laboratory of Cell Hemostasis, National Medical Research Centre of Cardiology Named after Academician E.I. Chazov of the Ministry of Health of the Russian Federation, 121552 Moscow, Russia.
Laboratory of Gas Exchange, Biomechanics and Barophysiology, State Scientific Center of the Russian Federation-The Institute of Biomedical Problems of the Russian Academy of Sciences, 123007 Moscow, Russia.

Olga Saburova (O)

Laboratory of Cell Hemostasis, National Medical Research Centre of Cardiology Named after Academician E.I. Chazov of the Ministry of Health of the Russian Federation, 121552 Moscow, Russia.

Konstantin Guria (K)

Laboratory of Cell Hemostasis, National Medical Research Centre of Cardiology Named after Academician E.I. Chazov of the Ministry of Health of the Russian Federation, 121552 Moscow, Russia.

Evgeny Matroze (E)

Laboratory of Cell Hemostasis, National Medical Research Centre of Cardiology Named after Academician E.I. Chazov of the Ministry of Health of the Russian Federation, 121552 Moscow, Russia.
Department of Innovative Pharmacy, Medical Devices and Biotechnology, Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.

Zufar Gabbasov (Z)

Laboratory of Cell Hemostasis, National Medical Research Centre of Cardiology Named after Academician E.I. Chazov of the Ministry of Health of the Russian Federation, 121552 Moscow, Russia.

Classifications MeSH