Chromosome Y Haplogroup R Was Associated with the Risk of Premature Myocardial Infarction with ST-Elevation: Data from the CholeSTEMI Registry.
cardiovascular risk factors
coronary artery disease
genetics
myocardial infarction
premature cardiovascular disease
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
21 Jul 2023
21 Jul 2023
Historique:
received:
21
06
2023
revised:
11
07
2023
accepted:
18
07
2023
medline:
29
7
2023
pubmed:
29
7
2023
entrez:
29
7
2023
Statut:
epublish
Résumé
Cardiovascular disease (CVD) is the leading cause of death worldwide, with coronary artery disease (CAD) being one of its main manifestations. Both environmental and genetic factors are widely known to be related to CAD, such as smoking, diabetes mellitus, dyslipidemia, and a family history of CAD. However, there is still a lack of information about other risk factors, especially those related to genetic mutations. Sex represents a classic CAD risk factor, as men are more likely to suffer CAD, but there is lack of evidence with regard to sex-specific genetic factors. We evaluated the Y chromosome haplogroups in a cohort of young Spanish male patients who suffered from STEMI. In this cohort, haplogroup R was significantly more frequent in STEMI patients.
Identifiants
pubmed: 37510926
pii: jcm12144812
doi: 10.3390/jcm12144812
pmc: PMC10381015
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Instituto de Salud Carlos III
ID : PI22/00705
Références
Annu Rev Genet. 2013;47:75-95
pubmed: 23988118
Hum Genet. 2012 Jul;131(7):1173-85
pubmed: 22271044
Atherosclerosis. 2014 Mar;233(1):160-4
pubmed: 24529138
Semin Vasc Med. 2004 Feb;4(1):59-65
pubmed: 15199434
Matrix Biol. 2015 May-Jul;44-46:157-66
pubmed: 25636537
Mol Cell Endocrinol. 2016 May 15;427:86-91
pubmed: 26970180
Eur Heart J. 2019 Jan 14;40(3):237-269
pubmed: 30165617
Nat Rev Genet. 2003 Aug;4(8):598-612
pubmed: 12897772
J Clin Med. 2020 Oct 29;9(11):
pubmed: 33137929
J Intern Med. 2002 Sep;252(3):247-54
pubmed: 12270005
J Am Coll Cardiol. 2013 Oct 22;62(17):1541-51
pubmed: 23973684
Curr Opin Lipidol. 2016 Oct;27(5):473-83
pubmed: 27472409
Circ Res. 2016 Feb 19;118(4):564-78
pubmed: 26892958
Arterioscler Thromb Vasc Biol. 2022 Sep;42(9):1198-1206
pubmed: 35861954
Circulation. 2009 Jan 6;119(1):116-22
pubmed: 19103996
Circ Cardiovasc Qual Outcomes. 2021 Jan;14(1):e005623
pubmed: 33397121
Lancet. 2012 Mar 10;379(9819):915-922
pubmed: 22325189
Eur Heart J. 2021 Sep 7;42(34):3227-3337
pubmed: 34458905
Eur Heart J. 2021 Apr 7;42(14):1289-1367
pubmed: 32860058
Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2386-2401
pubmed: 31644355
Nat Genet. 2000 Nov;26(3):358-61
pubmed: 11062480
Lancet. 2004 Sep 11-17;364(9438):937-52
pubmed: 15364185
Am J Cardiol. 1993 Jul 15;72(2):171-6
pubmed: 8328379
Am J Hum Genet. 2008 Dec;83(6):725-36
pubmed: 19061982
Eur J Hum Genet. 2010 Apr;18(4):479-84
pubmed: 19888303
J Clin Med. 2023 Mar 08;12(6):
pubmed: 36983136
J Am Coll Cardiol. 2019 Sep 10;74(10):1376-1414
pubmed: 30894319