Differences in Fecal Short-Chain Fatty Acids between Alcoholic Fatty Liver-Induced Cirrhosis and Non-alcoholic (Metabolic-Associated) Fatty Liver-Induced Cirrhosis.

gut microbiota gut–liver axis liver cirrhosis short-chain fatty acids

Journal

Metabolites
ISSN: 2218-1989
Titre abrégé: Metabolites
Pays: Switzerland
ID NLM: 101578790

Informations de publication

Date de publication:
19 Jul 2023
Historique:
received: 21 06 2023
revised: 14 07 2023
accepted: 18 07 2023
medline: 29 7 2023
pubmed: 29 7 2023
entrez: 29 7 2023
Statut: epublish

Résumé

The objective of this study was to investigate the metabolic activity of the gut microbiota in cirrhosis due to different variants of fatty liver disease (alcoholic vs. non-alcoholic [metabolic-associated] one [AFLD and MAFLD]). The present study included 24 patients with alcoholic liver cirrhosis, 16 patients with MAFLD-related cirrhosis, and 20 healthy controls. The level and spectrum of short-chain fatty acids (SCFAs) were determined via gas-liquid chromatography. All patients with cirrhosis showed a decrease in the total content of SCFAs (

Identifiants

pubmed: 37512565
pii: metabo13070859
doi: 10.3390/metabo13070859
pmc: PMC10383050
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Xinlu Cao (X)

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, 119435 Moscow, Russia.

Oksana Zolnikova (O)

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, 119435 Moscow, Russia.

Roman Maslennikov (R)

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, 119435 Moscow, Russia.
The Interregional Public Organization "Scientific Community for the Promotion of the Clinical Study of the Human Microbiome", 119121 Moscow, Russia.

Maria Reshetova (M)

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, 119435 Moscow, Russia.

Elena Poluektova (E)

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, 119435 Moscow, Russia.
The Interregional Public Organization "Scientific Community for the Promotion of the Clinical Study of the Human Microbiome", 119121 Moscow, Russia.

Arina Bogacheva (A)

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, 119435 Moscow, Russia.

Maria Zharkova (M)

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, 119435 Moscow, Russia.

Vladimir Ivashkin (V)

Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, 119435 Moscow, Russia.

Classifications MeSH