Engineered Lipidic Nanomaterials Inspired by Sphingomyelin Metabolism for Cancer Therapy.
cancer therapy
lipidic nanomaterial
sphingomyelin metabolism
tumor progression
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
12 Jul 2023
12 Jul 2023
Historique:
received:
17
05
2023
revised:
08
07
2023
accepted:
10
07
2023
medline:
31
7
2023
pubmed:
29
7
2023
entrez:
29
7
2023
Statut:
epublish
Résumé
Sphingomyelin (SM) and its metabolites are crucial regulators of tumor cell growth, differentiation, senescence, and programmed cell death. With the rise in lipid-based nanomaterials, engineered lipidic nanomaterials inspired by SM metabolism, corresponding lipid targeting, and signaling activation have made fascinating advances in cancer therapeutic processes. In this review, we first described the specific pathways of SM metabolism and the roles of their associated bioactive molecules in mediating cell survival or death. We next summarized the advantages and specific applications of SM metabolism-based lipidic nanomaterials in specific cancer therapies. Finally, we discussed the challenges and perspectives of this emerging and promising SM metabolism-based nanomaterials research area.
Identifiants
pubmed: 37513239
pii: molecules28145366
doi: 10.3390/molecules28145366
pmc: PMC10383197
pii:
doi:
Substances chimiques
Sphingomyelins
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Key Research and Development Program of China
ID : 2019YFA0210500
Organisme : National Natural Science Foundation of China
ID : Nos. 21977054
Organisme : National Natural Science Foundation of China
ID : Nos. 21877102
Organisme : National Natural Science Foundation of China
ID : Nos. 91953107
Références
Int J Oncol. 2011 Aug;39(2):425-31
pubmed: 21617856
Int J Cancer. 2009 Dec 1;125(11):2728-36
pubmed: 19521959
FEBS Lett. 2002 Oct 30;531(1):38-46
pubmed: 12401200
Bioorg Med Chem Lett. 2012 Apr 15;22(8):2794-7
pubmed: 22429468
Sci Rep. 2021 Aug 26;11(1):17213
pubmed: 34446776
Gastroenterology. 2018 Mar;154(4):1024-1036.e9
pubmed: 29408569
Science. 2019 Oct 18;366(6463):
pubmed: 31624181
Biophys J. 2006 Mar 15;90(6):2086-92
pubmed: 16387761
DNA Cell Biol. 2011 Jun;30(6):407-12
pubmed: 21294641
Bioconjug Chem. 2022 Nov 16;33(11):2076-2087
pubmed: 36281902
CA Cancer J Clin. 2016 Jul;66(4):271-89
pubmed: 27253694
Eur J Med Chem. 2022 Jan 5;227:113923
pubmed: 34688013
Biochem J. 1988 Sep 15;254(3):765-71
pubmed: 2848498
Oncotarget. 2016 May 3;7(18):24995-5009
pubmed: 27107419
Circ Res. 2001 Sep 14;89(6):496-502
pubmed: 11557736
Indian J Cancer. 2014 Oct-Dec;51(4):524-9
pubmed: 26842184
Cell Death Differ. 2004 Aug;11(8):853-61
pubmed: 15088070
Angew Chem Int Ed Engl. 2014 Nov 10;53(46):12320-64
pubmed: 25294565
Nanomaterials (Basel). 2021 Dec 14;11(12):
pubmed: 34947740
Cancer Cell. 2006 Mar;9(3):225-38
pubmed: 16530706
Trends Endocrinol Metab. 2007 Oct;18(8):300-7
pubmed: 17904858
Am J Transl Res. 2021 May 15;13(5):4412-4421
pubmed: 34150023
Mol Cancer Ther. 2006 Feb;5(2):200-8
pubmed: 16505092
J Biol Chem. 2011 Dec 9;286(49):42446-42458
pubmed: 22013072
Oncotarget. 2020 Feb 04;11(5):523-534
pubmed: 32082486
Prostate. 2007 Nov 1;67(15):1699-717
pubmed: 17879964
Cell Signal. 2005 Oct;17(10):1203-17
pubmed: 16038795
Int J Pharm. 2022 Jun 10;621:121788
pubmed: 35504431
Cancer Invest. 2012 Jan;30(1):27-37
pubmed: 22236187
J Nanobiotechnology. 2020 Jan 28;18(1):22
pubmed: 31992302
Bioorg Chem. 2019 Mar;84:444-455
pubmed: 30576908
Breast Cancer Res Treat. 2012 Jun;133(2):447-58
pubmed: 21935601
Nat Rev Cancer. 2013 Jan;13(1):51-65
pubmed: 23235911
J Clin Invest. 2002 Jul;110(1):3-8
pubmed: 12093880
J Pharmacol Exp Ther. 2003 Nov;307(2):468-75
pubmed: 12975495
Cancer Chemother Pharmacol. 2010 Oct;66(5):999-1003
pubmed: 20521051
Cancers (Basel). 2020 Dec 14;12(12):
pubmed: 33327621
Adv Cancer Res. 2018;140:61-96
pubmed: 30060817
Nat Commun. 2022 Jan 10;13(1):124
pubmed: 35013261
Cancers (Basel). 2021 May 19;13(10):
pubmed: 34069611
Int J Pharm. 2022 Apr 5;617:121577
pubmed: 35167901
Oncol Lett. 2015 Nov;10(5):3073-3080
pubmed: 26722292
Exp Cell Res. 2007 May 15;313(9):1877-85
pubmed: 17428472
Probiotics Antimicrob Proteins. 2020 Mar;12(1):311-319
pubmed: 30788662
Nat Nanotechnol. 2021 Oct;16(10):1130-1140
pubmed: 34385682
J Biol Chem. 2011 Aug 12;286(32):28544-55
pubmed: 21669879
ACS Cent Sci. 2019 Oct 23;5(10):1648-1662
pubmed: 31660434
Cell Biol Int. 2018 Jul;42(7):823-831
pubmed: 29369436
Int J Cancer. 2021 Apr 5;:
pubmed: 33818764
Traffic. 2008 Sep;9(10):1757-75
pubmed: 18694456
Biomed Pharmacother. 2021 Jul;139:111565
pubmed: 33887691
Nat Rev Endocrinol. 2020 Apr;16(4):224-233
pubmed: 32060415
Mater Horiz. 2023 Feb 6;10(2):466-472
pubmed: 36468425
J Am Chem Soc. 2019 Sep 11;141(36):14356-14363
pubmed: 31469268
Br J Pharmacol. 2015 Jan;172(1):106-18
pubmed: 25176316
Pharmaceutics. 2021 Sep 18;13(9):
pubmed: 34575588
EMBO J. 2004 Jan 14;23(1):33-44
pubmed: 14685263
J Leukoc Biol. 1994 Nov;56(5):533-41
pubmed: 7964160
Adv Exp Med Biol. 2010;688:1-23
pubmed: 20919643
AAPS PharmSciTech. 2019 Feb 4;20(3):99
pubmed: 30719596
Biochim Biophys Acta. 1969 Mar 4;176(2):339-47
pubmed: 5775951
Pharmacol Rep. 2016 Jun;68(3):570-81
pubmed: 26940196
Biophys J. 2003 Mar;84(3):1507-17
pubmed: 12609857
Nano Lett. 2008 Dec;8(12):4116-21
pubmed: 19367878
Nat Rev Mol Cell Biol. 2008 Feb;9(2):139-50
pubmed: 18216770
J Biol Chem. 1999 Jan 8;274(2):1140-6
pubmed: 9873062
Toxicol Appl Pharmacol. 1997 Jan;142(1):208-25
pubmed: 9007051
Mol Cancer Ther. 2018 Jan;17(1):50-59
pubmed: 29079707
J Biol Chem. 2011 Jul 15;286(28):25352-62
pubmed: 21613224
Prostaglandins Other Lipid Mediat. 2001 Apr;64(1-4):123-34
pubmed: 11324702
Br J Haematol. 2020 Aug;190(3):405-417
pubmed: 32124438
Cancer Res. 2002 Nov 1;62(21):6312-7
pubmed: 12414662
Int J Mol Sci. 2017 Sep 02;18(9):
pubmed: 28869494
Cancer Sci. 2020 Jul;111(7):2259-2274
pubmed: 32391585
Antioxid Redox Signal. 2007 Sep;9(9):1449-56
pubmed: 17576160
Exp Cell Res. 2015 May 1;333(2):195-200
pubmed: 25770011
FASEB J. 2020 Mar;34(3):3838-3854
pubmed: 31970839
Cell Biochem Biophys. 2014 Mar;68(2):359-67
pubmed: 23943053
J Biol Chem. 1990 May 25;265(15):8650-7
pubmed: 2187869
Nat Rev Drug Discov. 2007 Mar;6(3):231-48
pubmed: 17330072
Oncotarget. 2017 Jul 12;8(38):63923-63934
pubmed: 28969041
Trends Mol Med. 2007 May;13(5):210-7
pubmed: 17416206
Cell. 1996 Jul 26;86(2):189-99
pubmed: 8706124
Cancer Res. 2004 May 15;64(10):3593-8
pubmed: 15150117
Cancer Res. 2008 Oct 15;68(20):8635-42
pubmed: 18922940
Science. 2009 Sep 4;325(5945):1254-7
pubmed: 19729656
Nanoscale. 2020 Sep 21;12(35):18463-18475
pubmed: 32941570
Breast Cancer Manag. 2015 Oct;4(5):241-244
pubmed: 27293484
Biochem Cell Biol. 2004 Feb;82(1):27-44
pubmed: 15052326
Prog Lipid Res. 2013 Oct;52(4):424-37
pubmed: 23684760
Biochem Biophys Res Commun. 2001 Jun 22;284(4):1016-30
pubmed: 11409897
Blood. 2000 Nov 15;96(10):3431-8
pubmed: 11071638
Cell Signal. 2021 Nov;87:110119
pubmed: 34418535
Adv Enzyme Regul. 2011;51(1):51-8
pubmed: 21035485
Acta Pharmacol Sin. 2021 Jan;42(1):149-159
pubmed: 32451413
Nat Rev Cancer. 2004 Aug;4(8):604-16
pubmed: 15286740
Mol Ther. 2008 Sep;16(9):1565-71
pubmed: 18628757
Chemistry. 2018 Dec 20;24(72):19179-19194
pubmed: 30362192
Cancer Res. 2018 Apr 1;78(7):1713-1725
pubmed: 29351902
FASEB J. 2015 Nov;29(11):4654-69
pubmed: 26209696
Pharmacol Ther. 2019 Mar;195:85-99
pubmed: 30347210
Nat Commun. 2020 Aug 27;11(1):4279
pubmed: 32855410
Subcell Biochem. 2008;49:413-40
pubmed: 18751921
Int J Mol Sci. 2019 Nov 30;20(23):
pubmed: 31801289
J Biol Chem. 2007 Jun 22;282(25):18141-18150
pubmed: 17392276
Nature. 2003 Dec 18;426(6968):803-9
pubmed: 14685229
Science. 1996 Dec 13;274(5294):1855-9
pubmed: 8943189
Oncotarget. 2016 May 3;7(18):26780-92
pubmed: 27050145
Adv Mater. 2021 Jul;33(30):e2101701
pubmed: 34106489
Adv Drug Deliv Rev. 2013 Nov;65(13-14):1686-98
pubmed: 24055719
Endocrinology. 2009 Oct;150(10):4484-92
pubmed: 19706837
Biochim Biophys Acta. 2006 Dec;1758(12):2027-36
pubmed: 17161984
Pharm Res. 2014 Sep;31(9):2490-502
pubmed: 24643932
J Biol Chem. 2001 Apr 20;276(16):12797-804
pubmed: 11278937
Biochim Biophys Acta. 2016 Feb;1858(2):304-10
pubmed: 26656158
Cancer Biol Ther. 2011 Oct 1;12(7):574-85
pubmed: 21795855
J Cell Biol. 2009 Jun 15;185(6):1013-27
pubmed: 19506037
Apoptosis. 2015 Jul;20(7):960-74
pubmed: 25846011
Angew Chem Int Ed Engl. 2009;48(5):872-97
pubmed: 19142939
Cancer Immunol Res. 2021 May;9(5):568-582
pubmed: 33727246
Nat Rev Cancer. 2018 Jan;18(1):33-50
pubmed: 29147025
Anticancer Drugs. 2013 Jun;24(5):473-83
pubmed: 23426175
Nat Rev Mol Cell Biol. 2018 Mar;19(3):175-191
pubmed: 29165427
Biochim Biophys Acta. 2002 Dec 30;1585(2-3):193-201
pubmed: 12531554
J Pharmacol Exp Ther. 2010 May;333(2):454-64
pubmed: 20179157
Nano Today. 2010 Apr 1;5(2):143-159
pubmed: 20543895
Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17384-9
pubmed: 17090686
Cell Rep. 2021 Nov 2;37(5):109957
pubmed: 34731610
Urology. 2002 Oct;60(4):562-8
pubmed: 12385907
Cancer Res. 2005 Dec 15;65(24):11667-75
pubmed: 16357178
J Cell Sci. 2017 Jan 15;130(2):360-371
pubmed: 27888218
Mol Pharm. 2013 Mar 4;10(3):1020-34
pubmed: 23379426
Prog Lipid Res. 2016 Jan;61:51-62
pubmed: 26703189
Lipids Health Dis. 2021 Oct 31;20(1):150
pubmed: 34717628
Biochim Biophys Acta. 2006 Mar;1761(3):281-91
pubmed: 16631405
Colloids Surf B Biointerfaces. 2020 Dec;196:111357
pubmed: 32992284
Front Oncol. 2021 Oct 19;11:745092
pubmed: 34737957
Anticancer Res. 2014 Jul;34(7):3271-83
pubmed: 24982331
Oncotarget. 2016 Dec 6;7(49):80943-80956
pubmed: 27821815
J Biol Chem. 1999 Apr 9;274(15):10654-60
pubmed: 10187863
Signal Transduct Target Ther. 2021 May 31;6(1):201
pubmed: 34054126
Cancer Res. 2013 Dec 1;73(23):6972-86
pubmed: 24145350
Pharmaceutics. 2020 Feb 22;12(2):
pubmed: 32098309
Cancer Chemother Pharmacol. 2013 Mar;71(3):635-45
pubmed: 23263160
Mol Cell Biol. 2006 Oct;26(19):7211-23
pubmed: 16980623
J Lipid Res. 2010 Nov;51(11):3299-305
pubmed: 20671299
J Neurosci Res. 2004 Jan 1;75(1):66-74
pubmed: 14689449
Biochim Biophys Acta. 2006 Dec;1758(12):2016-26
pubmed: 16996023
Curr Pharm Des. 2022;28(4):313-323
pubmed: 32679012
Nat Med. 2018 Sep;24(9):1459-1468
pubmed: 30104766
Curr Pharm Des. 2006;12(35):4625-35
pubmed: 17168766
Cell Death Differ. 2010 Apr;17(4):642-54
pubmed: 19779494
Biomolecules. 2014 Mar 14;4(1):315-53
pubmed: 24970218
Cell Death Dis. 2019 Feb 15;10(3):157
pubmed: 30770781
Int J Mol Sci. 2019 Sep 02;20(17):
pubmed: 31480728
EMBO Mol Med. 2013 Jan;5(1):105-21
pubmed: 23180565
Chem Phys Lipids. 1999 Nov;102(1-2):29-34
pubmed: 11001558