Effects of Signal Peptide and Chaperone Co-Expression on Heterologous Protein Production in
chaperone
heterologous proteins
productivity
signal peptides
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
23 Jul 2023
23 Jul 2023
Historique:
received:
12
06
2023
revised:
17
07
2023
accepted:
21
07
2023
medline:
31
7
2023
pubmed:
29
7
2023
entrez:
29
7
2023
Statut:
epublish
Résumé
Various host systems have been employed to increase the yield of recombinant proteins. However, some recombinant proteins were successfully produced at high yields but with no functional activities. To achieve both high protein yield and high activities, molecular biological strategies have been continuously developed. This work describes the effect of signal peptide (SP) and co-expression of molecular chaperones on the production of active recombinant protein in
Identifiants
pubmed: 37513466
pii: molecules28145594
doi: 10.3390/molecules28145594
pmc: PMC10384211
pii:
doi:
Substances chimiques
beta-Mannosidase
EC 3.2.1.25
Molecular Chaperones
0
Escherichia coli Proteins
0
Recombinant Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Walailak University
ID : WU-IRG-63-036
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