The cancer preventive activity and mechanisms of prenylated resveratrol and derivatives.
Anticancer activity
Antioxidant activity
Caspase
ROS
Resveratrol
Journal
Current research in toxicology
ISSN: 2666-027X
Titre abrégé: Curr Res Toxicol
Pays: Netherlands
ID NLM: 101771915
Informations de publication
Date de publication:
2023
2023
Historique:
received:
04
06
2023
revised:
03
07
2023
accepted:
11
07
2023
medline:
31
7
2023
pubmed:
31
7
2023
entrez:
31
7
2023
Statut:
epublish
Résumé
Resveratrol is regarded as neutraceuticals with multiple health benefits. The introduction of prenyl can enhance the bioactivity. In this work, the cancer preventive activities and mechanisms of 18 prenylated reseveratrol and derivatives were investigated. The results showed that prenyl increased the antiproliferative activities of resveratrol, oxyresveratrol and piceatannol against cancer cells, and their antiproliferative activities were time- and dose-dependent. 4-C-prenylation was important for the antiproliferative activity of stilbenoids. The 4-
Identifiants
pubmed: 37519844
doi: 10.1016/j.crtox.2023.100113
pii: S2666-027X(23)00011-7
pmc: PMC10382290
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100113Informations de copyright
© 2023 The Author(s).
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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