AAV-

Cellular neuroscience Human genetics Molecular neuroscience

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
21 Jul 2023
Historique:
received: 22 03 2023
revised: 18 05 2023
accepted: 26 06 2023
medline: 31 7 2023
pubmed: 31 7 2023
entrez: 31 7 2023
Statut: epublish

Résumé

Loss of function of progranulin (PGRN), encoded by the

Identifiants

pubmed: 37519899
doi: 10.1016/j.isci.2023.107247
pii: S2589-0042(23)01324-X
pmc: PMC10371829
doi:

Types de publication

Journal Article

Langues

eng

Pagination

107247

Informations de copyright

© 2023 The Author(s).

Déclaration de conflit d'intérêts

The authors T.F., P.L., H.X.Q., and F.H. declare that they have no conflict of interest. M.K., A.M., G.M., G.W. J.P., K.P., A.K., H.L., and N.D. are/were employees of Alector and may have an equity interest in Alector, Inc.

Références

Nucleic Acids Res. 2011 Nov 1;39(20):8677-88
pubmed: 21785136
Acta Neuropathol. 2014 Mar;127(3):397-406
pubmed: 24385136
Mol Ther Methods Clin Dev. 2020 Oct 20;19:447-458
pubmed: 33294493
Anticancer Res. 2002 Nov-Dec;22(6A):3325-30
pubmed: 12530082
Biotechnol Bioeng. 2012 Aug;109(8):2093-103
pubmed: 22896849
Nat Commun. 2018 Jul 16;9(1):2731
pubmed: 30013069
Front Behav Neurosci. 2015 Jul 02;9:152
pubmed: 26190981
Cell. 2016 May 5;165(4):921-35
pubmed: 27114033
Mol Neurodegener. 2014 Sep 20;9:38
pubmed: 25239657
Sci Rep. 2018 Apr 30;8(1):6775
pubmed: 29712920
Brain. 2011 Mar;134(Pt 3):808-15
pubmed: 21354975
Neurobiol Aging. 2016 May;41:200.e1-200.e5
pubmed: 27021778
EMBO J. 2014 Mar 3;33(5):450-67
pubmed: 24357581
Acta Neuropathol. 2015 Mar;129(3):429-47
pubmed: 25631124
eNeuro. 2017 Aug 18;4(4):
pubmed: 28828399
EMBO Rep. 2020 Oct 5;21(10):e50197
pubmed: 32761777
Protein Cell. 2010 Jun;1(6):552-62
pubmed: 21204008
Front Immunol. 2021 Apr 13;12:666666
pubmed: 33927727
J Neurosci. 2012 Aug 15;32(33):11213-27
pubmed: 22895706
Am J Pathol. 2010 Jul;177(1):311-24
pubmed: 20522652
Science. 2009 Jul 24;325(5939):473-7
pubmed: 19556463
Nature. 2010 Jul 29;466(7306):622-6
pubmed: 20613723
Mol Neurodegener. 2017 Jul 25;12(1):55
pubmed: 28743268
Science. 2015 Jul 3;349(6243):70-4
pubmed: 26138975
J Biol Chem. 2012 Jun 1;287(23):19355-65
pubmed: 22511793
Mol Neurobiol. 2013 Feb;47(1):337-60
pubmed: 23239020
Am J Pathol. 2011 Jan;178(1):284-95
pubmed: 21224065
Cell. 2021 Sep 2;184(18):4651-4668.e25
pubmed: 34450028
Acta Neuropathol. 2014;127(6):845-60
pubmed: 24619111
Sci Transl Med. 2017 Apr 12;9(385):
pubmed: 28404863
Biotechnol Bioeng. 2011 Nov;108(11):2670-81
pubmed: 21618470
Mol Cell Neurosci. 2014 Jul;61:226-40
pubmed: 25066864
Cell Rep. 2020 Mar 10;30(10):3506-3519.e6
pubmed: 32160553
J Exp Med. 2010 Jan 18;207(1):117-28
pubmed: 20026663
Signal Transduct Target Ther. 2021 Feb 8;6(1):53
pubmed: 33558455
J Mol Biol. 2019 Mar 1;431(5):1038-1047
pubmed: 30690031
Mol Neurodegener. 2012 Jul 10;7:33
pubmed: 22781549
Brain. 2019 Jun 1;142(6):1503-1527
pubmed: 31039256
Sci Rep. 2015 Nov 19;5:16952
pubmed: 26581326
Biotechnol Bioeng. 2012 Jul;109(7):1713-22
pubmed: 22234778
Acta Neuropathol. 2017 Jul;134(1):151-153
pubmed: 28493053
Hum Mol Genet. 2017 Dec 15;26(24):4861-4872
pubmed: 29036611
Neurology. 2011 Feb 1;76(5):467-74
pubmed: 21178100
Nat Commun. 2022 Oct 7;13(1):5924
pubmed: 36207292
Mol Neurodegener. 2017 Aug 23;12(1):62
pubmed: 28835281
Hum Mol Genet. 2013 Feb 15;22(4):685-95
pubmed: 23136129
Brain Pathol. 2021 Mar;31(2):223-238
pubmed: 33016371
Neuropharmacology. 2017 Jul 1;120:63-80
pubmed: 26905292
Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5785-5794
pubmed: 30833387
Lancet Neurol. 2019 Dec;18(12):1091-1102
pubmed: 31701892
Trends Pharmacol Sci. 2022 Aug;43(8):641-652
pubmed: 35039149
Neuroscience. 2013 Oct 10;250:8-19
pubmed: 23830905
Hum Gene Ther. 2011 Sep;22(9):1143-53
pubmed: 21476867
Brain. 2020 Jun 1;143(6):1905-1919
pubmed: 32504082
Front Neuroanat. 2019 Nov 26;13:93
pubmed: 31849618
Bioessays. 2009 Nov;31(11):1245-54
pubmed: 19795409
Curr Opin Neurobiol. 2022 Feb;72:131-139
pubmed: 34826653
Trends Cell Biol. 2023 Apr;33(4):324-339
pubmed: 36244875
Brain Commun. 2022 Jan 04;4(1):fcab310
pubmed: 35169707
Nat Rev Neurosci. 2017 Jun;18(6):325-333
pubmed: 28435163
Neuroscience. 2013 Feb 12;231:49-60
pubmed: 23201826
PLoS One. 2011;6(6):e21023
pubmed: 21698296
Acta Neuropathol Commun. 2022 Mar 14;10(1):33
pubmed: 35287730
J Mol Neurosci. 2011 Nov;45(3):538-48
pubmed: 21691802
Brain Res Rev. 2011 Jun 24;67(1-2):252-9
pubmed: 21356243
Gene Ther. 2021 Dec;28(12):683-696
pubmed: 33658649
J Neurosci. 2013 Mar 20;33(12):5352-61
pubmed: 23516300
Nucleic Acids Res. 1999 Dec 15;27(24):4775-82
pubmed: 10572178
PLoS One. 2019 Jul 10;14(7):e0212382
pubmed: 31291241
EBioMedicine. 2016 Sep;11:127-137
pubmed: 27515686
Hum Mol Genet. 2006 Oct 15;15(20):2988-3001
pubmed: 16950801
Curr Opin Neurobiol. 2020 Apr;61:40-48
pubmed: 31863938
Nat Genet. 2010 Mar;42(3):234-9
pubmed: 20154673
J Cell Biol. 2008 Apr 7;181(1):37-41
pubmed: 18378771
Mol Ther. 2018 Feb 7;26(2):510-523
pubmed: 29175157
J Neurosci. 2018 Feb 28;38(9):2341-2358
pubmed: 29378861
J Biotechnol. 2010 Jun;147(3-4):180-5
pubmed: 20430058
EMBO Rep. 2020 Oct 5;21(10):e50219
pubmed: 32852886
Brain. 2020 Jul 1;143(7):2255-2271
pubmed: 32572497
Nat Commun. 2017 May 25;8:15277
pubmed: 28541286
J Biol Chem. 2012 Sep 21;287(39):32298-306
pubmed: 22859297
Adv Exp Med Biol. 2021;1281:219-242
pubmed: 33433878
Biomedicines. 2022 May 15;10(5):
pubmed: 35625877
Mol Ther. 2011 Jan;19(1):16-27
pubmed: 21119617
Brain. 2017 May 1;140(5):1447-1465
pubmed: 28379303
Am J Hum Genet. 2012 Jun 8;90(6):1102-7
pubmed: 22608501
Ann Clin Transl Neurol. 2020 Oct;7(10):1843-1853
pubmed: 32937039
Hum Mol Genet. 2020 Mar 27;29(5):716-726
pubmed: 31600775
Nature. 2006 Aug 24;442(7105):916-9
pubmed: 16862116
Acta Neuropathol Commun. 2019 Dec 23;7(1):218
pubmed: 31870439
Epilepsia. 2014 Jun;55(6):e56-9
pubmed: 24779634
Hum Mol Genet. 2017 Aug 1;26(15):2850-2863
pubmed: 28453791
J Cell Biol. 2015 Sep 14;210(6):991-1002
pubmed: 26370502
Nature. 2006 Aug 24;442(7105):920-4
pubmed: 16862115
Mol Ther. 2019 Feb 6;27(2):465-478
pubmed: 30559071
Arch Neurol. 2011 May;68(5):581-6
pubmed: 21220649
Acta Neuropathol Commun. 2014 Jul 15;2:78
pubmed: 25022663
Int J Mol Sci. 2020 Oct 29;21(21):
pubmed: 33137979
Sci Rep. 2014 Jul 01;4:5506
pubmed: 24981028
Acta Neuropathol. 2021 Mar;141(3):327-339
pubmed: 33386471
EMBO Rep. 2020 Oct 5;21(10):e50241
pubmed: 32929860
Gene Ther. 2001 Oct;8(20):1539-46
pubmed: 11704814
Neuron. 2017 Jul 19;95(2):281-296.e6
pubmed: 28728022
Brain Pathol. 2021 May;31(3):e12945
pubmed: 33709463
Neuron. 2010 Nov 18;68(4):654-67
pubmed: 21092856
Biochem Biophys Res Commun. 2010 Nov 12;402(2):228-34
pubmed: 20933502
Acta Neuropathol. 2018 Jul;136(1):1-17
pubmed: 29744576
Cell. 2016 Sep 8;166(6):1564-1571.e6
pubmed: 27610576
Sci Adv. 2023 May 5;9(18):eadd2676
pubmed: 37146150

Auteurs

Tuancheng Feng (T)

Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

Gregory Minevich (G)

Alector Inc, South San Francisco, CA 94080, USA.

Pengan Liu (P)

Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

Henry Xin Qin (HX)

Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

Glenn Wozniak (G)

Alector Inc, South San Francisco, CA 94080, USA.

Jenny Pham (J)

Alector Inc, South San Francisco, CA 94080, USA.

Khanh Pham (K)

Alector Inc, South San Francisco, CA 94080, USA.

Akshata Korgaonkar (A)

Alector Inc, South San Francisco, CA 94080, USA.

Michael Kurnellas (M)

Alector Inc, South San Francisco, CA 94080, USA.

Nadine A Defranoux (NA)

Alector Inc, South San Francisco, CA 94080, USA.

Hua Long (H)

Alector Inc, South San Francisco, CA 94080, USA.

Ananya Mitra (A)

Alector Inc, South San Francisco, CA 94080, USA.

Fenghua Hu (F)

Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

Classifications MeSH