Therapeutic efficacy of proton pump inhibitor (omeprazole) on cryptosporidiosis

Cryptosporidium parvum Nitazoxanide Omeprazole Proton pump inhibitor TEM Triosephosphate isomerase

Journal

Journal of parasitic diseases : official organ of the Indian Society for Parasitology
ISSN: 0971-7196
Titre abrégé: J Parasit Dis
Pays: India
ID NLM: 9713059

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 02 01 2023
accepted: 04 05 2023
pmc-release: 01 09 2024
medline: 31 7 2023
pubmed: 31 7 2023
entrez: 31 7 2023
Statut: ppublish

Résumé

Cryptosporidiosis is one of the most frequent food and water-borne diseases. The disease might be life-threatening in immunosuppressed patients. Unfortunately, the only approved drug, nitazoxanide, is with variable efficacies, particularly in malnourished children and immunocompromised patients. Therefore, there is a need to discover an alternative treatment that could be achieved by targeting the metabolic pathways. One of the important enzymes in the glycolysis pathway of

Identifiants

pubmed: 37520212
doi: 10.1007/s12639-023-01592-9
pii: 1592
pmc: PMC10382457
doi:

Types de publication

Journal Article

Langues

eng

Pagination

535-549

Informations de copyright

© Indian Society for Parasitology 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Déclaration de conflit d'intérêts

Conflict of interestThe authors declare that they have no conflict of interests.

Auteurs

Engy V N Beshay (EVN)

Medical Parasitology Department, Faculty of Medicine, Menoufia University, Yassin Abdel Gaffar St. from Gamal Abdel Nasser St., Shebin El-Kom, Menoufia Egypt.

Nashaat E Nassef (NE)

Medical Parasitology Department, Faculty of Medicine, Menoufia University, Yassin Abdel Gaffar St. from Gamal Abdel Nasser St., Shebin El-Kom, Menoufia Egypt.

Omaima K El Shafei (OK)

Medical Parasitology Department, Faculty of Medicine, Menoufia University, Yassin Abdel Gaffar St. from Gamal Abdel Nasser St., Shebin El-Kom, Menoufia Egypt.

Mona M Saleh (MM)

Medical Parasitology Department, Faculty of Medicine, Menoufia University, Yassin Abdel Gaffar St. from Gamal Abdel Nasser St., Shebin El-Kom, Menoufia Egypt.

Mona A Kora (MA)

Pathology Department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Menoufia Egypt.

Fatma H Shalaan (FH)

Medical Parasitology Department, Faculty of Medicine, Menoufia University, Yassin Abdel Gaffar St. from Gamal Abdel Nasser St., Shebin El-Kom, Menoufia Egypt.

Classifications MeSH