Selective Determination of Norfloxacin in Pharmaceutical Formulations and Human Urine Samples Using Poly(8-aminonaphthaline-2-sulfonic Acid)-Modified Glassy Carbon Electrodes.


Journal

ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658

Informations de publication

Date de publication:
25 Jul 2023
Historique:
received: 07 02 2023
accepted: 26 06 2023
medline: 31 7 2023
pubmed: 31 7 2023
entrez: 31 7 2023
Statut: epublish

Résumé

In this study, a glassy carbon electrode was modified potentiodynamically with poly(8-aminonaphthaline-2-sulfonic acid) [poly(ANSA)/GCE] for the detection of norfloxacin (NFN) in tablet formulations and human urine samples. Improvement of the effective surface area of the modified electrode and decreased charge-transfer resistance confirmed surface modification of the GCE by a conductive poly(ANSA) film. The appearance of an oxidative peak without a reductive peak in the reverse scan direction showed the irreversibility of the electrochemical oxidation of NFN in both the bare GCE and poly(ANSA)/GCE. A better coefficient of determination for the peak current on the square root of the scan rate (

Identifiants

pubmed: 37521652
doi: 10.1021/acsomega.3c00805
pmc: PMC10372944
doi:

Types de publication

Journal Article

Langues

eng

Pagination

25758-25765

Informations de copyright

© 2023 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Ameha Debalkie (A)

Department of Chemistry, College of Science, University of Gondar, Gondar 196, Ethiopia.

Atnafu Guadie (A)

Department of Chemistry, College of Science, University of Gondar, Gondar 196, Ethiopia.

Adane Kassa (A)

Department of Chemistry, College of Natural and Computational Sciences, Debre Markos University, Debre Markos 269, Ethiopia.
Department of Chemistry, College of Science, Bahir Dar University, Ethipia 79, Ethiopia.

Molla Tefera (M)

Department of Chemistry, College of Science, University of Gondar, Gondar 196, Ethiopia.

Classifications MeSH