Adult zebrafish as advanced models of human disease.


Journal

Disease models & mechanisms
ISSN: 1754-8411
Titre abrégé: Dis Model Mech
Pays: England
ID NLM: 101483332

Informations de publication

Date de publication:
01 08 2023
Historique:
medline: 1 8 2023
pubmed: 31 7 2023
entrez: 31 7 2023
Statut: ppublish

Résumé

Modelling adult diseases to understand their aetiology and progression, and to develop new therapies, is a major challenge for medical biology. We are excited by new efforts in the zebrafish community to develop models of adult diseases that range from cancer to heart, infectious and age-related diseases, and those that relate to toxicology and complex social behaviours. Here, we discuss some of the advances in the field of zebrafish models of adult disease, and where we see opportunities and challenges ahead.

Identifiants

pubmed: 37522272
pii: 324979
doi: 10.1242/dmm.050351
pmc: PMC10655866
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Medical Research Council
ID : MC_UU_00007/9
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_00035/13
Pays : United Kingdom

Informations de copyright

© 2023. Published by The Company of Biologists Ltd.

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Auteurs

Richard M White (RM)

Ludwig Cancer Institute, Nuffield Department of Medicine, Old Road Campus Research Building, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, UK.

E Elizabeth Patton (EE)

MRC Human Genetics Unit, CRUK Scotland Centre and Edinburgh Cancer Research, Institute of Genetics and Cancer, The University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh EH42XU, UK.

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Classifications MeSH