Single-cell profiling of muscle-infiltrating T cells in idiopathic inflammatory myopathies.
HOBIT
T-cell receptor
idiopathic inflammatory myopathies
muscle
tissue resident memory T cells
Journal
EMBO molecular medicine
ISSN: 1757-4684
Titre abrégé: EMBO Mol Med
Pays: England
ID NLM: 101487380
Informations de publication
Date de publication:
11 10 2023
11 10 2023
Historique:
revised:
04
07
2023
received:
29
11
2022
accepted:
10
07
2023
medline:
12
10
2023
pubmed:
31
7
2023
entrez:
31
7
2023
Statut:
ppublish
Résumé
Idiopathic inflammatory myopathies (IIM) are rare autoimmune systemic diseases characterized by muscle weakness and the presence of muscle-infiltrating T cells. IIM represent a clinical challenge due to heterogeneity of symptoms and variability of response to immunosuppressive treatment. Here, we performed in-depth single-cell sequencing on muscle-infiltrating T cells and peripheral blood memory T cells in six patients with recently diagnosed IIM. We identified tissue resident memory T-cell (T
Identifiants
pubmed: 37522383
doi: 10.15252/emmm.202217240
pmc: PMC10565639
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e17240Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2023 The Authors. Published under the terms of the CC BY 4.0 license.
Références
Arthritis Rheum. 2010 Nov;62(11):3457-66
pubmed: 20662057
Cell Rep. 2017 Sep 19;20(12):2921-2934
pubmed: 28930685
Nat Methods. 2013 Nov;10(11):1096-8
pubmed: 24056875
Arthritis Rheum. 2013 Dec;65(12):3063-72
pubmed: 24022618
Ann Rheum Dis. 2018 Jan;77(1):40-47
pubmed: 28814428
Sci Immunol. 2021 Aug 20;6(62):
pubmed: 34417257
Front Cell Dev Biol. 2018 Sep 04;6:108
pubmed: 30234113
Autoimmun Rev. 2022 Feb;21(2):102993
pubmed: 34798316
Nat Methods. 2016 Apr;13(4):329-332
pubmed: 26950746
Medicine (Baltimore). 2005 Jul;84(4):231-249
pubmed: 16010208
Trends Immunol. 2018 Dec;39(12):1021-1035
pubmed: 30413351
J Clin Invest. 1996 Jun 15;97(12):2905-10
pubmed: 8675705
Science. 2016 Apr 22;352(6284):459-63
pubmed: 27102484
J Rheumatol. 2001 Jul;28(7):1591-9
pubmed: 11469467
Muscle Nerve. 2012 May;45(5):676-83
pubmed: 22499094
Nat Commun. 2015 Sep 25;6:8306
pubmed: 26404698
Arthritis Rheum. 1999 Feb;42(2):291-8
pubmed: 10025923
Nat Immunol. 2013 Dec;14(12):1285-93
pubmed: 24162775
J Immunol. 2009 Sep 1;183(5):3481-7
pubmed: 19675166
Acta Neurol Scand. 1979 Jun;59(6):317-23
pubmed: 484204
Nat Commun. 2019 Oct 17;10(1):4706
pubmed: 31624246
Nat Methods. 2019 Dec;16(12):1289-1296
pubmed: 31740819
Science. 2022 Apr 15;376(6590):eabi9591
pubmed: 35258337
Nature. 2017 Feb 1;542(7639):110-114
pubmed: 28150777
Curr Opin Neurol. 1996 Jun;9(3):235-9
pubmed: 8839618
Am J Med. 1970 Jun;48(6):715-23
pubmed: 5420557
Nat Rev Rheumatol. 2018 May;14(5):269-278
pubmed: 29651121
Brain. 2019 Sep 1;142(9):2590-2604
pubmed: 31326977
Ann Rheum Dis. 2017 Dec;76(12):1955-1964
pubmed: 29079590
J Neuroimmunol. 2010 Aug 25;225(1-2):137-42
pubmed: 20537411
Ann Neurol. 1984 Aug;16(2):193-208
pubmed: 6383191
Ann Rheum Dis. 2016 Aug;75(8):1558-66
pubmed: 26362759
Ann Rheum Dis. 2019 Jul;78(7):996-1002
pubmed: 31138531
Ann Neurol. 1986 Feb;19(2):112-25
pubmed: 3008636
Clin Exp Rheumatol. 2020 Jan-Feb;38(1):42-49
pubmed: 31140400
F1000Res. 2016 Aug 31;5:2122
pubmed: 27909575
J Exp Med. 2014 Apr 7;211(4):623-33
pubmed: 24687959
Nature. 2003 Mar 13;422(6928):164-9
pubmed: 12634786
Rheumatology (Oxford). 2017 May 1;56(5):802-810
pubmed: 28160487
Sci Transl Med. 2014 Oct 15;6(258):258ra142
pubmed: 25320234
N Engl J Med. 1975 Feb 13;292(7):344-7
pubmed: 1090839
Nat Biotechnol. 2020 Jun;38(6):708-714
pubmed: 32518404
Nat Commun. 2022 Jul 13;13(1):4046
pubmed: 35831277
Nat Immunol. 2018 Mar;19(3):291-301
pubmed: 29434354
EMBO Mol Med. 2023 Oct 11;15(10):e17240
pubmed: 37522383
Cell. 2013 Dec 5;155(6):1282-95
pubmed: 24315098
J Exp Med. 1994 Sep 1;180(3):1171-6
pubmed: 8064234
Medicine (Baltimore). 1991 Nov;70(6):360-74
pubmed: 1659647
Genes Immun. 2015 Oct;16(7):470-80
pubmed: 26291516
Neurology. 2018 Feb 6;90(6):e507-e517
pubmed: 29330311
Sci Transl Med. 2022 Jun 15;14(649):eabo0686
pubmed: 35704599
Arthritis Res Ther. 2012 Dec 28;14(6):230
pubmed: 23270751
Cell Death Differ. 2021 Dec;28(12):3357-3370
pubmed: 34183782
Sci Rep. 2020 Jan 14;10(1):229
pubmed: 31937892
J Leukoc Biol. 2011 Oct;90(4):735-40
pubmed: 21724806
Gigascience. 2018 Jun 1;7(6):
pubmed: 29846586
Curr Treatm Opt Rheumatol. 2018;4(4):299-315
pubmed: 30613465
J Exp Med. 2019 Dec 2;216(12):2748-2762
pubmed: 31558615
Nat Biotechnol. 2015 May;33(5):495-502
pubmed: 25867923
J Exp Med. 2006 May 15;203(5):1343-55
pubmed: 16682498