Re-vaccination For Hepatitis B in Previous Non-Responders Following Hepatitis C Eradication.
Hepatitis B virus vaccine
direct-acting antiviral
hepatitis B virus vaccine nonresponse
hepatitis C virus
Journal
The Journal of infectious diseases
ISSN: 1537-6613
Titre abrégé: J Infect Dis
Pays: United States
ID NLM: 0413675
Informations de publication
Date de publication:
31 Jul 2023
31 Jul 2023
Historique:
received:
26
04
2023
revised:
11
07
2023
accepted:
28
07
2023
medline:
31
7
2023
pubmed:
31
7
2023
entrez:
31
7
2023
Statut:
aheadofprint
Résumé
Patients with chronic HCV do not respond to HBV vaccination as efficiently as the general population. We assessed if re-vaccination after HCV treatment resulted in improved response. Previous HBV vaccine non-responders were prospectively recruited for revaccination after HCV eradication. HBsAb testing was performed one month after series completion. Follow-up HBsAb testing was performed in 31 out of 34 enrolled patients with 21 (67.7%) reactive results. There were no significant differences in HBsAb reactivity based on age, sex, race, or advanced fibrosis presence. HBV vaccine non-responders should be considered for re-vaccination following HCV cure.
Identifiants
pubmed: 37523757
pii: 7234307
doi: 10.1093/infdis/jiad301
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.