Magnetically controlled drug delivery and hyperthermia effects of core-shell Cu@Mn
Cancer cells
Heat shock proteins
Magnetic fluid hyperthermia
Magnetic nanoparticles
Mn(3)O(4) coated cu
Sustainable cancer treatment
Theranostics
Journal
International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578
Informations de publication
Date de publication:
30 Sep 2023
30 Sep 2023
Historique:
received:
22
03
2023
revised:
28
05
2023
accepted:
28
07
2023
medline:
27
9
2023
pubmed:
1
8
2023
entrez:
31
7
2023
Statut:
ppublish
Résumé
Recent increase in the integration of nanotechnology and nanosciences to the biomedical sector fetches the human wellness through the development of sustainable treatment methodologies for cancerous tumors at all stages of their initiation and progression. This involves the development of multifunctional theranostic probes that effectively support for the early cancer diagnosis, avoiding non-target cell toxicity, controlled and customized anticancer drug release etc. Therefore, to advance the field of nanotechnology-based sustainable cancer treatment, we fabricated and tested the efficacy of anticancer drug-loaded magnetic hybrid nanoparticles (NPs) towards in vitro cell culture systems. The developed conjugate of NPs was incorporated with the functions of both controlled drug delivery and heat-releasing ability using Mn
Identifiants
pubmed: 37524291
pii: S0141-8130(23)02966-5
doi: 10.1016/j.ijbiomac.2023.126071
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
manganese oxide
64J2OA7MH3
Fluorouracil
U3P01618RT
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
126071Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.