Seroprevalence of leptospirosis among blood donors in an endemic area.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
31 07 2023
31 07 2023
Historique:
received:
22
03
2023
accepted:
25
07
2023
medline:
2
8
2023
pubmed:
1
8
2023
entrez:
31
7
2023
Statut:
epublish
Résumé
Thailand is known to be endemic for leptospirosis. This bacterium may pose a potential risk to transfusion safety. This study was a cross-sectional study examining the seroprevalence of leptospirosis among Thai blood donors. A total of 1053 serum specimens collected from blood donors residing in 5 regions of Thailand during March to September 2020 were included in this study. All samples were tested for the presence of antibodies to 22 leptospiral serovars using the microscopic agglutination test (MAT) and anti-Leptospira IgG antibodies using commercially available enzyme immunoassay. We found no evidence of recent exposure to Leptospira spp. in sera of healthy Thai blood donors by MAT, including those in higher-risk areas. However, in this same group, we did find small numbers of past exposure (1.7%) to Leptospira spp. by IgG ELISA. According to the findings of this study, there is currently no evidence for implementing new blood banking procedures to identify possible carriers in Thailand, however these should be continually monitored and revised according to the infectious disease burden in each country. It should be noted that there was a difference in the occupation rate between the general population reported in Thailand and blood donors in this study; it may not reflect the actual situation in the country.
Identifiants
pubmed: 37524788
doi: 10.1038/s41598-023-39461-3
pii: 10.1038/s41598-023-39461-3
pmc: PMC10390486
doi:
Substances chimiques
Antibodies, Bacterial
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
12336Informations de copyright
© 2023. The Author(s).
Références
J Clin Diagn Res. 2014 Jan;8(1):199-202
pubmed: 24596774
Int J Environ Res Public Health. 2014 Feb 05;11(2):1756-75
pubmed: 24503973
Am J Trop Med Hyg. 2019 Dec;101(6):1265-1271
pubmed: 31628737
J Transl Med. 2007 Jun 06;5:25
pubmed: 17553144
Ann Trop Med Parasitol. 2010 Oct;104(7):543-56
pubmed: 21092392
PLoS Negl Trop Dis. 2019 May 23;13(5):e0007270
pubmed: 31120895
PLoS Negl Trop Dis. 2021 Jul 1;15(7):e0009565
pubmed: 34197457
Clin Infect Dis. 2012 Aug;55(3):322-31
pubmed: 22523263
BMC Public Health. 2022 Dec 3;22(1):2260
pubmed: 36463162
PLoS One. 2021 Sep 29;16(9):e0257971
pubmed: 34587213
Comp Immunol Microbiol Infect Dis. 2020 Apr 29;71:101486
pubmed: 32438195
PLoS One. 2019 May 29;14(5):e0217643
pubmed: 31141558
Am J Trop Med Hyg. 2000 Sep-Oct;63(3-4):204-8
pubmed: 11388516
Lancet Infect Dis. 2020 Dec;20(12):1446-1456
pubmed: 32673593
Curr Top Microbiol Immunol. 2015;387:65-97
pubmed: 25388133
BMC Infect Dis. 2021 Nov 1;21(1):1128
pubmed: 34724919
Epidemiol Infect. 2022 Dec 27;151:e17
pubmed: 36572418
Trans R Soc Trop Med Hyg. 1966;60(3):361-5
pubmed: 5950685
Blood Transfus. 2015 Dec 01;14(6):504-508
pubmed: 26674831
Am J Trop Med Hyg. 2017 Dec;97(6):1682-1685
pubmed: 29016321
PLoS Negl Trop Dis. 2017 Feb 9;11(2):e0005228
pubmed: 28182662
Blood Transfus. 2015 Jan;13(1):32-6
pubmed: 24960651
Clin Microbiol Rev. 2001 Apr;14(2):296-326
pubmed: 11292640
Am J Trop Med Hyg. 2016 Sep 7;95(3):531-536
pubmed: 27402521
Blood Transfus. 2009 Jul;7(3):167-71
pubmed: 19657478
J Infect Dis. 2019 Sep 26;220(9):1489-1497
pubmed: 31342075
Transfusion. 2019 Mar;59(3):1035-1043
pubmed: 30443992
Transfusion. 2014 Dec;54(12):3232-41
pubmed: 24965017
Clin Infect Dis. 2022 Mar 9;74(5):871-881
pubmed: 34111244
PLoS Negl Trop Dis. 2015 Sep 17;9(9):e0003898
pubmed: 26379143
Epidemiol Infect. 2016 May;144(7):1550-62
pubmed: 26607833
Emerg Infect Dis. 2016 Jul;22(7):1221-8
pubmed: 27070192
Transfusion. 2017 Mar;57(3pt2):770-778
pubmed: 28229475
N Engl J Med. 2018 May 10;378(19):1778-1788
pubmed: 29742375
Sci Rep. 2021 Feb 5;11(1):3215
pubmed: 33547388
J Infect Dis. 2016 Jul 1;214(1):49-54
pubmed: 27302934