Development and validation of prognostic nomogram for T


Journal

BMC cancer
ISSN: 1471-2407
Titre abrégé: BMC Cancer
Pays: England
ID NLM: 100967800

Informations de publication

Date de publication:
31 Jul 2023
Historique:
received: 24 08 2022
accepted: 06 07 2023
medline: 2 8 2023
pubmed: 1 8 2023
entrez: 31 7 2023
Statut: epublish

Résumé

Radical resection plus lymph node dissection is a common treatment for patients with T This study involved 3002 patients with T Age, sex, histological classification, pathological T stage, and HI standard were independent factors for OS and were included in our nomogram. The C-index of the nomogram for OS estimates were 0.671 (95% CI, 0.637-0.705),0.632 (95% CI, 0.581-0.683), and 0.645 (95% CI, 0.617-0.673) in the training cohorts, internal validation cohorts, and external validation cohort, respectively. The calibration plots and DCA for predictions of OS were in excellent agreement. An online version of the nomogram was built for convenient clinical practice. Our nomogram can predict the OS of patients with T

Sections du résumé

BACKGROUND BACKGROUND
Radical resection plus lymph node dissection is a common treatment for patients with T
MATERIALS AND METHODS METHODS
This study involved 3002 patients with T
RESULTS RESULTS
Age, sex, histological classification, pathological T stage, and HI standard were independent factors for OS and were included in our nomogram. The C-index of the nomogram for OS estimates were 0.671 (95% CI, 0.637-0.705),0.632 (95% CI, 0.581-0.683), and 0.645 (95% CI, 0.617-0.673) in the training cohorts, internal validation cohorts, and external validation cohort, respectively. The calibration plots and DCA for predictions of OS were in excellent agreement. An online version of the nomogram was built for convenient clinical practice.
CONCLUSIONS CONCLUSIONS
Our nomogram can predict the OS of patients with T

Identifiants

pubmed: 37525124
doi: 10.1186/s12885-023-11158-w
pii: 10.1186/s12885-023-11158-w
pmc: PMC10391852
doi:

Types de publication

Randomized Controlled Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

715

Informations de copyright

© 2023. The Author(s).

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Auteurs

Weijian Mei (W)

Department of Thoracic Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, 510060, Guangdong, China.

Wang Yao (W)

Department of Interventional Oncology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

Zhengbo Song (Z)

Department of Medical Oncology, Cancer Hospital of University of Chinese Academy of Sciences; Zhejiang Cancer Hospital, Hangzhou, China.

Wenjie Jiao (W)

Department of Thoracic Surgery, Affiliated Hospital of Qingdao University, Qingdao, China.

Lianxin Zhu (L)

Medical College of Nanchang University, Nanchang, China.
Queen Mary University of London, London, UK.

Qinghua Huang (Q)

Department of Breast Surgery, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.

Chaolun An (C)

Department of Thoracic Surgery, Nantong Third People's Hospital Nantong University, Nantong, China.

Jianguang Shi (J)

Department of Thoracic Surgery, Ningbo First Hospital of Zhejiang University, Ningbo, China.

Guiping Yu (G)

Department of Thoracic Surgery, Affiliated Jiangyin Hospital of Southeast University, Jiangyin, China.

Pingli Sun (P)

Department of Pathology Department, The Second Hospital of Jilin University, Changchun, China.

Yinbin Zhang (Y)

Department of Thoracic Surgery, The Second Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, China.

Jianfei Shen (J)

Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou, China.

Chunwei Xu (C)

Department of Respiratory Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Suqian Hospital of Chinese Medicine, 9 Hongzehu Dong Road, Suqian, 223800, Jiangsu, China. xuchunweibbb@163.com.

Han Yang (H)

Department of Thoracic Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, 510060, Guangdong, China. yanghan@sysucc.org.cn.

Qian Wang (Q)

Department of Respiratory Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Suqian Hospital of Chinese Medicine, 9 Hongzehu Dong Road, Suqian, 223800, Jiangsu, China. wangqian1978@njucm.edu.cn.

Zhihua Zhu (Z)

Department of Thoracic Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, 510060, Guangdong, China. zhuzhh@sysucc.org.cn.

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