A nanotherapeutic approach to selectively eliminate metastatic breast cancer cells by targeting cell surface GRP78.

Animals Mice Endoplasmic Reticulum Chaperone BiP Membrane Proteins Cell Line, Tumor Prodrugs Glucose Peptides Doxorubicin / pharmacology Neoplasms

Journal

Nanoscale
ISSN: 2040-3372
Titre abrégé: Nanoscale
Pays: England
ID NLM: 101525249

Informations de publication

Date de publication:
17 Aug 2023
Historique:
medline: 21 8 2023
pubmed: 1 8 2023
entrez: 1 8 2023
Statut: epublish

Résumé

Here, rational engineering of doxorubicin prodrug loaded peptide-targeted liposomal nanoparticles to selectively target metastatic breast cancer cells

Identifiants

DOI: 10.1039/d3nr00800b PMID: 37526009
pubmed: 37526009
doi: 10.1039/d3nr00800b
doi:

Substances chimiques

Endoplasmic Reticulum Chaperone BiP 0
Membrane Proteins 0
Prodrugs 0
Glucose IY9XDZ35W2
Peptides 0
Doxorubicin 80168379AG

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

13322-13334

Auteurs

Jaeho Shin (J)

Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 465567, USA. bbilgicer@nd.edu.

Baksun Kim (B)

Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 465567, USA. bbilgicer@nd.edu.

Tyson W Lager (TW)

Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.

Franklin Mejia (F)

Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 465567, USA. bbilgicer@nd.edu.

Ian Guldner (I)

Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA.

Clay Conner (C)

Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.

Siyuan Zhang (S)

Department of Pathology, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75235, USA.

Athanasia D Panopoulos (AD)

Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA.
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.
Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. athanasia.panopoulos@cshs.org.
Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
ORCID: 0000-0002-9610-2604

Basar Bilgicer (B)

Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 465567, USA. bbilgicer@nd.edu.
Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA.
Berthiaume Institute for Precision Health, University of Notre Dame, Notre Dame, IN 46556, USA.
ORCID: 0000-0002-4134-2547

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › A nanotherapeutic approach to selectively...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A nanotherapeutic approach to selectively...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Chaperons moléculaires › Protéines du choc thermique › Protéines du choc thermique HSP70 › Chaperonne BiP du réticulum endoplasmique › A nanotherapeutic approach to selectively...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › A nanotherapeutic approach to selectively...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › A nanotherapeutic approach to selectively...
questionsmedicales.fr › Préparations pharmaceutiques › Promédicaments › A nanotherapeutic approach to selectively...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › A nanotherapeutic approach to selectively...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › A nanotherapeutic approach to selectively...
questionsmedicales.fr › Glucides › Hétérosides › Aminosides › Anthracyclines › Daunorubicine › Doxorubicine › A nanotherapeutic approach to selectively...
questionsmedicales.fr › Tumeurs › A nanotherapeutic approach to selectively...