Techniques and Complications of Anesthesia in Pediatric Radiotherapy: A Retrospective Cohort Study.


Journal

Journal of pediatric hematology/oncology
ISSN: 1536-3678
Titre abrégé: J Pediatr Hematol Oncol
Pays: United States
ID NLM: 9505928

Informations de publication

Date de publication:
01 Oct 2023
Historique:
received: 21 11 2022
accepted: 15 05 2023
pubmed: 1 8 2023
medline: 1 8 2023
entrez: 1 8 2023
Statut: ppublish

Résumé

Anesthesia during pediatric external beam radiation therapy poses a challenge, as radiotherapy rooms are not designed for the administration of anesthesia. We conducted a retrospective cohort study of children who underwent radiation therapy to describe the anesthetic approach and assess anesthetic-related complications. Data of all, who underwent radiation therapy under general anesthesia between November 2019 and January 2021, were recorded. Data were obtained from medical records, including demographic characteristics and information, regarding the anesthetic procedure and its associated complications. We describe our protocols for preoperative assessment, anesthetic procedures, and postanesthetic discharge evaluation. Over the reporting period, 739 sessions of general anesthesia were performed. The mean number of radiation therapy rounds per patient was 23.5 sessions. Anesthetic induction was accomplished by sevoflurane inhalation in 639 sessions (86.4%) and intravenous propofol in the remaining 13.6%. General anesthesia was maintained with sevoflurane in all cases. Anesthesia-related complications occurred in 118 sessions (15.7%). The most frequent was nausea in 48 (6.4%) cases, followed by hypotension in 38 (5.1%). Airway-related complications occurred at a low frequency (2.3%), and all were resolved successfully with positive pressure ventilation. No patient hospitalizations were required because of any anesthetic complications. Inhalation anesthesia is reliable and safe for pediatric patients undergoing radiation therapy.

Sections du résumé

BACKGROUND BACKGROUND
Anesthesia during pediatric external beam radiation therapy poses a challenge, as radiotherapy rooms are not designed for the administration of anesthesia.
AIMS OBJECTIVE
We conducted a retrospective cohort study of children who underwent radiation therapy to describe the anesthetic approach and assess anesthetic-related complications.
MATERIALS AND METHODS METHODS
Data of all, who underwent radiation therapy under general anesthesia between November 2019 and January 2021, were recorded. Data were obtained from medical records, including demographic characteristics and information, regarding the anesthetic procedure and its associated complications. We describe our protocols for preoperative assessment, anesthetic procedures, and postanesthetic discharge evaluation.
RESULTS RESULTS
Over the reporting period, 739 sessions of general anesthesia were performed. The mean number of radiation therapy rounds per patient was 23.5 sessions. Anesthetic induction was accomplished by sevoflurane inhalation in 639 sessions (86.4%) and intravenous propofol in the remaining 13.6%. General anesthesia was maintained with sevoflurane in all cases. Anesthesia-related complications occurred in 118 sessions (15.7%). The most frequent was nausea in 48 (6.4%) cases, followed by hypotension in 38 (5.1%). Airway-related complications occurred at a low frequency (2.3%), and all were resolved successfully with positive pressure ventilation. No patient hospitalizations were required because of any anesthetic complications.
CONCLUSIONS CONCLUSIONS
Inhalation anesthesia is reliable and safe for pediatric patients undergoing radiation therapy.

Identifiants

pubmed: 37526351
doi: 10.1097/MPH.0000000000002706
pii: 00043426-990000000-00264
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

377-382

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Nicolás Villablanca (N)

Anesthesia Unit, National Cancer Institute, Santiago, Chile.

Nicolás Valls (N)

Anesthesia Unit, National Cancer Institute, Santiago, Chile.

Roberto González (R)

Anesthesia Unit, National Cancer Institute, Santiago, Chile.
Department of Anesthesiology and Perioperattive Medicine, University of Chile Santiago, Chile.

Classifications MeSH