Work ability and work status changes in long-term Hodgkin lymphoma survivors with focus on late adverse effects.
Cancer survivors
Late adverse effects
Work ability; Hodgkin lymphoma
Journal
Journal of cancer survivorship : research and practice
ISSN: 1932-2267
Titre abrégé: J Cancer Surviv
Pays: United States
ID NLM: 101307557
Informations de publication
Date de publication:
01 Aug 2023
01 Aug 2023
Historique:
received:
23
02
2023
accepted:
14
07
2023
medline:
1
8
2023
pubmed:
1
8
2023
entrez:
1
8
2023
Statut:
aheadofprint
Résumé
We studied work-related issues in long-term survivors of Hodgkin lymphoma [HLSs] who had undergone treatment according to contemporary stage risk-adapted approaches. At survey, work changes and problems since diagnosis, comparisons of HLSs with low/moderate versus high work ability, associations between work issues, and late adverse effects [LAEs] were examined. This cross-sectional questionnaire-based study included HLSs treated from 1997 to 2006 and alive at the end of 2016. They completed a mailed questionnaire including work and health-related issues. Among 518 invited HLSs, 297 (58%) completed the work-related issues, and 48% of them were females. Mean age at survey was 45.9 years, and mean time was 16.7 years since diagnosis. At follow-up, 71% of the HLSs held paid work and 19% were on disability pension. Only 3% of HLSs did not hold paid work at any time after diagnosis. In total, 43% HLSs had low/moderate and 57% high work ability at follow-up. Low/moderate work ability was significantly associated with older age, female sex, more LAEs, disability pension, lower household income, distressed personality, obesity, fatigue, and mental disorders. More LAEs were significantly associated with more work problems. Many HLSs manage to stay in the work force. Several health problems and LAEs amenable for interventions are significantly associated with low/moderate work ability and emphasize the importance of focus on these issues in long-term follow-up. HLSs in paid work at diagnosis can be optimistic as to their future participation in work life. Screening and treatment for health problems such as LAEs may improve work ability.
Identifiants
pubmed: 37526861
doi: 10.1007/s11764-023-01432-y
pii: 10.1007/s11764-023-01432-y
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2023. The Author(s).
Références
de Boer AGEM, Torp S, Popa A, et al. Long-term work retention after treatment of cancer: a systematic review and meta-analysis. J Cancer Surviv. 2020;14(2):135–50.
doi: 10.1007/s11764-020-00862-2
pubmed: 32162193
pmcid: 7182621
Mehnert A, de Boer A, Feuerstein M. Employment challenges for cancer survivors. Cancer. 2013;119(Suppl 11):2151–9.
doi: 10.1002/cncr.28067
pubmed: 23695927
Ng AK, van Leeuwen FE. Hodgkin lymphoma: late effects of treatment and guidelines for surveillance. Semin Hematol. 2016;53(3):209–15.
doi: 10.1053/j.seminhematol.2016.05.008
pubmed: 27496313
Pálmarsdóttir R, Øvlisen AK, Severinsen MT, et al. Socioeconomic impact of Hodgkin lymphoma in adult patients: a systematic literature review. Leuk Lymphoma. 2019;60(13):3116–31.
doi: 10.1080/10428194.2019.1613538
pubmed: 31167589
Juul SJ, Rossetti S, Kicinski M, et al. Employment situation among long-term Hodgkin lymphoma survivors in Europe: an analysis of patients from nine consecutive EORTC-LYSA trials. J Cancer Surviv. 2022. https://doi.org/10.1007/s11764-022-01305-w . (online ahead of print)
Hoersboel TA, Nielsen CV, Nielsen B, et al. Type of hematological malignancy is crucial for the return to work prognosis: a register-based cohort study. J Cancer Surviv. 2013;7(4):614–23.
doi: 10.1007/s11764-013-0300-z
Hoersboel TA, Nielsen CV, Andersen NT, et al. Risk of disability pension for patients diagnosed with hematological malignancies: a register-based cohort study. Acta Oncol. 2014;53(6):724–34.
doi: 10.3109/0284186X.2013.875625
Glimelius I, Ekberg S, Linderoth J, et al. Sick leave and disability pension in Hodgkin lymphoma survivors by stage, treatment, and follow-up time—a population based comparative study. J Cancer Surviv. 2015;9(4):599–609.
doi: 10.1007/s11764-015-0436-0
pubmed: 25689964
Kiserud CE, Fagerli U-M, Smeland KB, et al. Patterns of employment and associated factors in long-term lymphoma survivors 10 years after high-dose chemotherapy with autologous stem-cell transplantation. Acta Oncol. 2016;55(5):547–53.
doi: 10.3109/0284186X.2015.1125015
pubmed: 27123741
Ilmarinen J, Tuomi K, Seitsamo J. New dimensions of work ability. Int Congr Ser. 2005;1280:3–7.
doi: 10.1016/j.ics.2005.02.060
Tuomi K, Ilmarinen J, Jakhola A, et al. Work Ability Index. 2nd edition. Helsinki: Finnish Institute of Occupational Health, 2006.
Ahlstrom L, Grimsby-Ekman A, et al. The work ability index and single-item question: associations with sick leave, symptoms, and health–—a prospective study of women on long-term sick leave. Scand J Work Environ Health. 2010;36(5):404–12.
doi: 10.5271/sjweh.2917
pubmed: 20372766
Jääskeläinen A, Kausto J, Seitsamo J, et al. Work ability index and perceived work ability as predictors of disability pension: a prospective study among Finnish municipal employees. Scand J Work Environ Health. 2016;42(6):490–9.
doi: 10.5271/sjweh.3598
pubmed: 27706492
Boelhouwer IG, Vermeer W, van Vuuren T. The associations between late effects of cancer treatment, work ability and job resources: a systematic review. Int Arch Occup Environ Health. 2021;94(2):147–89.
doi: 10.1007/s00420-020-01567-w
pubmed: 32929528
Taskila T, Martikainen R, Hietanen P, et al. Comparative study of work ability between cancer survivors and their referents. Eur J Cancer. 2007;43(5):914–20.
doi: 10.1016/j.ejca.2007.01.012
pubmed: 17314041
Torp S, Syse J, Paraponaris A, et al. Return to work among self-employed cancer survivors. J Cancer Surviv. 2017;11(2):189–200.
doi: 10.1007/s11764-016-0578-8
pubmed: 27837444
Eikeland SA, Smeland KB, Mols F, et al. Chemotherapy-induced peripheral neuropathy after modern treatment of Hodgkin’s lymphoma: symptom burden and quality of life. Acta Oncol. 2021;60(7):911–20.
doi: 10.1080/0284186X.2021.1917776
pubmed: 33905285
Denollet J. DS14: Standard assessment of negative affectivity, social inhibition, and type D personality. Psychosom Med. 2005;67(1):89–97.
doi: 10.1097/01.psy.0000149256.81953.49
pubmed: 15673629
McAdams DP, Pals JL. A new big five. Fundamental principles for an integrative science of personality. Am Psychol. 2006;61(3):204–17.
doi: 10.1037/0003-066X.61.3.204
pubmed: 16594837
Mols F, Oerlemans S, Denollet J, et al. Type D personality is associated with increased comorbidity burden and health care utilization among 3080 cancer survivors. Gen Hosp Psychiatry. 2012;34(4):352–9.
doi: 10.1016/j.genhosppsych.2012.01.014
pubmed: 22459997
Mols F, Thong MSY, van de Poll-Franse LV, et al. Type D personality is associated with poor quality of life and mental health among 3080 cancer survivors. J Affect Disord. 2012;136(1-2):26–34.
doi: 10.1016/j.jad.2011.08.034
pubmed: 21943928
Chalder T, Berelowitz G, Pawlikowska T, et al. Development of a fatigue scale. J Psychosom Res. 1993;37(2):147–53.
doi: 10.1016/0022-3999(93)90081-P
pubmed: 8463991
Dahl AA, Grotmol KS, Hjermstad MJ, et al. Norwegian reference data on the Fatigue Questionnaire and the Patient Health Questionnaire-9 and their interrelationship. Ann General Psychiatry. 2020;19:60.
doi: 10.1186/s12991-020-00311-5
Thoresen S, Tambs K, Hussain A, et al. Brief measure of posttraumatic stress reactions: Impact of Event Scale-6. Soc Psychiatry Psychiatr Epidemiol. 2010;45(3):405–12.
doi: 10.1007/s00127-009-0073-x
pubmed: 19479171
Kroenke K, Spitzer RL, Williams JBW. The PHQ-9: validity of a brief depression severity measure. J Intern Med. 2001;16(9):606–13.
Holmen J, Langballe EM, Midthjell K, et al. Gender differences in subjective memory impairment in a general population: the HUNT study, Norway. BMC Psychol. 2013;9:19.
doi: 10.1186/2050-7283-1-19
Ganz PA. Survivorship: adult cancer survivors. Prim Care. 2009;36(4):721–41.
doi: 10.1016/j.pop.2009.08.001
pubmed: 19913184
Hudson MM, Ness K-K, Gurney JG, et al. Clinical ascertainment of health outcomes among adults treated for childhood cancer. JAMA. 2013;309(22):2371–81.
doi: 10.1001/jama.2013.6296
pubmed: 23757085
pmcid: 3771083
Kiserud CE, Dahl AA, Loge JH, et al. Cancer survivorship in adults. Recent Results Cancer Res. 2014;197:103–20.
doi: 10.1007/978-3-642-40187-9_8
pubmed: 24305772
Duijts SFA. Management of work through the seasons of cancer survivorship. Curr Opin Support Palliat Care. 2018;12(1):80–5.
doi: 10.1097/SPC.0000000000000320
pubmed: 29176331
Syse A, Tretli S, Kravdal Ø. Cancer’s impact on employment and earnings—a population-based study from Norway. J Cancer Surviv. 2008;2(3):149–58.
doi: 10.1007/s11764-008-0053-2
pubmed: 18792789
Syse A, Tretli S, Kravdal Ø. The impact of cancer on spouses’ labor earnings: a population-based study. Cancer. 2009;115(18 Suppl):4350–61.
doi: 10.1002/cncr.24582
pubmed: 19731350
Whitney RL, Bell JF, Reed SC, et al. Predictors of financial difficulties and work modifications among cancer survivors in the United States. J Cancer Surviv. 2016;10(2):241–50.
doi: 10.1007/s11764-015-0470-y
pubmed: 26188363
Grov EK, Fosså SD, Bremnes RM, et al. The personality trait of neuroticism is strongly associated with long-term morbidity in testicular cancer survivors. Acta Oncol. 2009;48(6):842–9.
doi: 10.1080/02841860902795232
pubmed: 19412812
Dahl AA. Link between personality and cancer. Future Oncol. 2010;6(5):691–707.
doi: 10.2217/fon.10.31
pubmed: 20465385
Simensen VC, Smeland KB, Kiserud CE, et al. Survivors’ knowledge of their diagnosis, treatment and possible late adverse effects after autologous stem cell transplantation for lymphoma. Acta Oncol. 2019;58(9):1315–22.
doi: 10.1080/0284186X.2019.1637538
pubmed: 31286808
Lange M, Joly F, Vardy J, et al. Cancer-related cognitive impairment: an update on state of the art, detection, and management strategies in cancer survivors. Ann Oncol. 2019;30(12):1925–40.
doi: 10.1093/annonc/mdz410
pubmed: 31617564
Mols F, Denollet J. Type D personality in the general population: a systematic review of health status, mechanisms of disease, and work-related problems. Health Qual Life Outcomes. 2010;8:9.
doi: 10.1186/1477-7525-8-9
pubmed: 20096129
pmcid: 2822747
Bleidorn W, Hill PL, Back MD, et al. The policy relevance of personality traits. Am Psychol. 2019;74(9):1056–67.
doi: 10.1037/amp0000503
pubmed: 31829685