New insights in lower limb reconstruction strategies.

fracture-related infection high energy musculoskeletal traumas limb reconstruction limb salvage mal union non-union osteomyelitis

Journal

Therapeutic advances in musculoskeletal disease
ISSN: 1759-720X
Titre abrégé: Ther Adv Musculoskelet Dis
Pays: England
ID NLM: 101517322

Informations de publication

Date de publication:
2023
Historique:
received: 11 04 2023
accepted: 04 07 2023
medline: 2 8 2023
pubmed: 2 8 2023
entrez: 2 8 2023
Statut: epublish

Résumé

High Energy Musculoskeletal Traumas (HEMTs) represent a relevant problem for healthcare systems, considering the high social costs, and both the high morbidity and mortality. The poor outcomes associated with HEMT are related to the high incidence of complications, including bone infection, fracture malunion and non-union. The treatment of each of these complications could be extremely difficult. Limb reconstruction often needs multiple procedures, rising some questions on the opportunity in perseverate to try to save the affected limb. In fact, theoretically, amputation may guarantee better function and lower complications. However, amputation is not free of complication, and a high long-term social cost has been reported. A comprehensive literature review was performed to suggest possible ways to optimize the limb preservation surgeries of HEMT's complications in order to ameliorate their management.

Identifiants

pubmed: 37529331
doi: 10.1177/1759720X231189008
pii: 10.1177_1759720X231189008
pmc: PMC10387789
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1759720X231189008

Informations de copyright

© The Author(s), 2023.

Déclaration de conflit d'intérêts

The authors declare that there is no conflict of interest.

Références

JAMA Surg. 2016 Nov 16;151(11):e162775
pubmed: 27603155
Clin Microbiol Infect. 2016 May;22(5):457.e1-9
pubmed: 26806134
BMC Musculoskelet Disord. 2023 Mar 11;24(1):184
pubmed: 36906529
Clin Orthop Relat Res. 2015 Sep;473(9):2848-55
pubmed: 26028596
Surg Clin North Am. 2017 Oct;97(5):1119-1131
pubmed: 28958361
Clin Orthop Relat Res. 2014 Dec;472(12):3892-901
pubmed: 24777722
Int J Surg Case Rep. 2017;39:102-105
pubmed: 28826070
Injury. 2021 Jun;52(6):1641-1645
pubmed: 33568278
J Orthop Traumatol. 2019 Apr 11;20(1):21
pubmed: 30976944
Infection. 2020 Jun;48(3):333-344
pubmed: 32270441
J Bone Joint Surg Am. 2012 Jun 20;94(12):1057-64
pubmed: 22572980
Eur J Pharmacol. 2021 Oct 15;909:174409
pubmed: 34364879
Clin Orthop Relat Res. 2003 Sep;(414):7-24
pubmed: 12966271
Arch Orthop Trauma Surg. 2020 Aug;140(8):1013-1027
pubmed: 31659475
J Clin Orthop Trauma. 2018 Mar;9(Suppl 1):S103-S105
pubmed: 29628709
Orthop Clin North Am. 2016 Apr;47(2):365-75
pubmed: 26772945
Ann Surg. 1905 Feb;41(2):249-51
pubmed: 17861599
J Orthop Res. 2017 Sep;35(9):1845-1854
pubmed: 28387956
Medicina (Kaunas). 2022 Feb 17;58(2):
pubmed: 35208632
Injury. 2019 Jul;50 Suppl 2:S75-S79
pubmed: 30846284
Lancet. 2001 Jul 14;358(9276):135-8
pubmed: 11463434
Injury. 2006 Apr;37 Suppl 1:S41-50
pubmed: 16581074
Injury. 2017 Oct;48(10):2276-2284
pubmed: 28734494
Injury. 2008 Sep;39 Suppl 2:S59-63
pubmed: 18804575
EFORT Open Rev. 2018 May 21;3(5):316-325
pubmed: 29951271
J Clin Orthop Trauma. 2021 Apr 19;18:20-24
pubmed: 33987079
Clin Cases Miner Bone Metab. 2017 Jan-Apr;14(1):28-34
pubmed: 28740522
Microsurgery. 2002;22(5):187-92
pubmed: 12210963
Orthopade. 2020 Aug;49(8):702-709
pubmed: 32671414
J Orthop Trauma. 2017 Feb;31(2):111-119
pubmed: 27611666
Int J Infect Dis. 2019 Apr;81:128-136
pubmed: 30772469
BMC Infect Dis. 2013 Jan 29;13:47
pubmed: 23356488
Strategies Trauma Limb Reconstr. 2014 Aug;9(2):89-96
pubmed: 25056513
J Reconstr Microsurg. 2017 Oct;33(S 01):S20-S26
pubmed: 28985635
J Clin Orthop Trauma. 2020 Jul;11(Suppl 4):S578-S584
pubmed: 32774032
World J Surg. 2020 Apr;44(4):1033-1038
pubmed: 30043200
Bioelectromagnetics. 2020 Jul;41(5):323-337
pubmed: 32495506
J Am Acad Orthop Surg. 2003 Sep-Oct;11(5):302-11
pubmed: 14565752
J Bone Joint Surg Am. 2010 Sep;92 Suppl 1 Pt 2:158-75
pubmed: 20844172
J Clin Orthop Trauma. 2019 Nov-Dec;10(6):1128-1131
pubmed: 31708640
Int J Antimicrob Agents. 2008 Aug;32(2):154-7
pubmed: 18571387
Int Orthop. 2021 Jul;45(7):1827-1835
pubmed: 33876255
Injury. 2020 Jul;51(7):1419-1421
pubmed: 32553413
Injury. 2021 Jun;52 Suppl 2:S3-S11
pubmed: 33221036
J Orthop Surg Res. 2022 Jul 15;17(1):347
pubmed: 35840981
Curr Infect Dis Rep. 2008 Sep;10(5):394-403
pubmed: 18687204
Bone Joint J. 2016 Sep;98-B(9):1289-96
pubmed: 27587534
Infect Immun. 2020 Jun 22;88(7):
pubmed: 32094258
Clin Cases Miner Bone Metab. 2017 May-Aug;14(2):186-188
pubmed: 29263731
Indian J Orthop. 2012 Nov;46(6):653-8
pubmed: 23325967
Stem Cells Int. 2019 Dec 27;2019:3715964
pubmed: 31949437
JBJS Essent Surg Tech. 2021 Jul 14;11(3):
pubmed: 34650830
J Am Acad Orthop Surg. 2008 Jul;16(7):369-75
pubmed: 18611994
Curr Microbiol. 2015 May;70(5):698-703
pubmed: 25586078
Medicina (Kaunas). 2020 Aug 07;56(8):
pubmed: 32784812
J Biomed Mater Res A. 2019 Feb;107(2):301-311
pubmed: 29673055
Trauma Case Rep. 2022 Jan 31;38:100609
pubmed: 35141388
J Orthop Trauma. 2009 Jan;23(1):1-6
pubmed: 19104297
Injury. 2019 Dec;50 Suppl 5:S40-S45
pubmed: 31708086
Strategies Trauma Limb Reconstr. 2012 Aug;7(2):67-72
pubmed: 22729940
Drug Deliv. 2021 Dec;28(1):2392-2414
pubmed: 34755579
Arch Orthop Trauma Surg. 2019 Jan;139(1):61-72
pubmed: 30343322
Medicina (Kaunas). 2020 Nov 23;56(11):
pubmed: 33238390
Front Surg. 2022 Nov 03;9:938595
pubmed: 36406375
Clin Microbiol Infect. 2019 Jan;25(1):76-81
pubmed: 29649599
APMIS. 2017 Apr;125(4):353-364
pubmed: 28407423
Clin Orthop Relat Res. 1990 Jan;(250):81-104
pubmed: 2403498
J Orthop Trauma. 2018 Oct;32(10):e415-e420
pubmed: 30247286
Injury. 2019 Jun;50 Suppl 1:S73-S78
pubmed: 30955871
Injury. 2007 Mar;38 Suppl 1:S100-7
pubmed: 17383479
Br J Hosp Med (Lond). 2013 Oct;74(10):577-80
pubmed: 24105311
J Orthop Sci. 2019 May;24(3):387-392
pubmed: 30797666
Transl Med UniSa. 2014 Sep 01;12:47-53
pubmed: 26535187
J Orthop Trauma. 2020 Jan;34(1):30-41
pubmed: 31567902
Int Orthop. 2018 Feb;42(2):247-258
pubmed: 29273837
Int Orthop. 2010 Feb;34(2):255-61
pubmed: 19547973
J Clin Orthop Trauma. 2020 Feb;11(Suppl 1):S107-S112
pubmed: 31992929
J Bone Jt Infect. 2017 Jan 1;2(1):38-51
pubmed: 28529863
Orthop Traumatol Surg Res. 2018 Apr;104(2):277-281
pubmed: 29407071
Eur J Orthop Surg Traumatol. 2022 Aug;32(6):1119-1126
pubmed: 34363107
Eur J Trauma Emerg Surg. 2019 Feb;45(1):13-19
pubmed: 28577203
Injury. 2014 Dec;45 Suppl 6:S93-7
pubmed: 25457326
Osteoporos Int. 2005 Mar;16 Suppl 2:S36-43
pubmed: 15372141
Handchir Mikrochir Plast Chir. 2019 Dec;51(6):453-463
pubmed: 31698488
Injury. 2018 Mar;49(3):511-522
pubmed: 27639601
J Bone Jt Infect. 2018 Aug 10;3(4):173-181
pubmed: 30155402
Int Orthop. 2017 Dec;41(12):2457-2469
pubmed: 28831576
Bioorg Med Chem Lett. 2010 Feb 15;20(4):1355-9
pubmed: 20097069
Clin Orthop Relat Res. 2008 Feb;466(2):466-72
pubmed: 18196433
Clin Microbiol Infect. 2020 May;26(5):652-653
pubmed: 32087322
Clin Interv Aging. 2020 Mar 26;15:485-491
pubmed: 32273690
Injury. 2017 Jul;48(7):1339-1347
pubmed: 28532896
Clin Biomech (Bristol, Avon). 2018 Nov;59:181-198
pubmed: 30268996
Injury. 2015 Dec;46 Suppl 8:S1-2
pubmed: 26747912
Injury. 2014 Jul;45(7):1025-7
pubmed: 24794617
J Surg Orthop Adv. 2020 Summer;29(3):129-134
pubmed: 33044151
Injury. 2018 Mar;49(3):505-510
pubmed: 28867644
J Biomed Mater Res B Appl Biomater. 2022 Jul;110(7):1724-1749
pubmed: 35156317

Auteurs

Giuseppe Toro (G)

Department of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples, Italy.

Antonio Benedetto Cecere (AB)

Unit of Orthopaedics and Traumatology, San Giuliano Hospital, Giugliano in Campania, Naples, Italy.

Adriano Braile (A)

Department of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Via L. De Crecchio, 4. Naples 80138, Italy Unit of Orthopaedics and Traumatology, Ospedale del Mare, Naples, Italy.

Annalisa De Cicco (A)

Department of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples, Italy Unit of Orthopaedics and Traumatology, Santa Maria delle Grazie Hospital, Pozzuoli, Italy.

Sara Liguori (S)

Department of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples, Italy.

Umberto Tarantino (U)

Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy.

Giovanni Iolascon (G)

Department of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Naples, Italy.

Classifications MeSH