Delphi expert consensus for whole slide imaging in thyroid cytopathology.
Delphi method
consensus panel
digital pathology
thyroid cytopathology
validation
whole slide imaging
Journal
Cytopathology : official journal of the British Society for Clinical Cytology
ISSN: 1365-2303
Titre abrégé: Cytopathology
Pays: England
ID NLM: 9010345
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
revised:
05
07
2023
received:
07
06
2023
accepted:
14
07
2023
pubmed:
2
8
2023
medline:
2
8
2023
entrez:
2
8
2023
Statut:
ppublish
Résumé
Despite an increase in thyroid fine needle aspiration (FNA) and advances in whole slide imaging (WSI) adoption, digital pathology is still considered inadequate for primary diagnosis of these cases. Herein, we aim to validate the utility of WSI in thyroid FNAs employing the Delphi method strategy. A panel of experts from seven reference cytology centres was recruited. The study consisted of two consecutive rounds: (1) an open-ended, free-response questionnaire generating a list of survey items; and (2) a consensus analysis of 80 selected shared WSIs from 80 cases by six investigators answering six morphological questions utilising a 1 to 5 Likert scale. High consensus was achieved for all parameters, with an overall average score of 4.27. The broad majority of items (84%) were ranked either 4 or 5 by each physician. Two badly scanned cases were responsible for more than half of the low-ranked (≤2) values (57%). Good to excellent (≥3) diagnostic confidence was reached in more than 95.2% of cases. For most cases (78%) WSI assessment was not limited by technical issues linked to the image acquisition process. This systematic Delphi study indicates broad consensus among participating physicians on the application of DP to thyroid cytopathology, supporting expert opinion that WSI is reliable and safe for primary diagnostic purposes.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
581-589Subventions
Organisme : Italian Minister of University MUR Dipartimenti di Eccellenza 2023-2027 (l. 232/2016, art. 1, commi 314 - 337) and grant RF GR-2019-12368592
Informations de copyright
© 2023 The Authors. Cytopathology published by John Wiley & Sons Ltd.
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