Unmasking Heterogeneity of Sleep Apnea.

Heart rate response to events Hypoxic burden Obstructive sleep apnea Risk factors for OSA Symptoms of OSA

Journal

Sleep medicine clinics
ISSN: 1556-4088
Titre abrégé: Sleep Med Clin
Pays: United States
ID NLM: 101271531

Informations de publication

Date de publication:
Sep 2023
Historique:
medline: 4 8 2023
pubmed: 3 8 2023
entrez: 2 8 2023
Statut: ppublish

Résumé

Sleep apnea is heterogeneous in multiple dimensions. There are different physiological risk factors that may have clinical relevance. However, assessing them is challenging. An approach to ascertain them using a simple model of ventilatory control has been proposed. It is based, however, on untenable assumptions. There are limited validation data and reproducibility is not stellar. There are also different symptom subtypes. They have been found in multiple population-based and clinical cohorts worldwide. Symptomatic benefit from therapy is most marked in the excessively sleepy subtype. This group may also be the group at increased CV risk from obstructive sleep apnea.

Identifiants

pubmed: 37532370
pii: S1556-407X(23)00036-X
doi: 10.1016/j.jsmc.2023.05.003
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

293-299

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Allan I Pack (AI)

Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Perelman School of Medicine, 125 South 31st Street, Translational Resesarch Laboratories, Suite 2100, Philadelphia, PA 19104, USA. Electronic address: pack@pennmedicine.upenn.edu.

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Classifications MeSH