Early-onset Cervical Myelitis after COVID-19 Vaccination.
COVID-19 mRNA vaccine
cervical myelitis
immunopathological preexisting susceptibility
Journal
Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241
Informations de publication
Date de publication:
15 Oct 2023
15 Oct 2023
Historique:
medline:
15
11
2023
pubmed:
3
8
2023
entrez:
2
8
2023
Statut:
ppublish
Résumé
A 33-year-old woman developed paresthesia in her right thumb approximately 30 minutes after receiving the BNT162b2 (Pfizer-BioNTech) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine. The paresthesia gradually spread to her right-side limbs and trunk, and cervical magnetic resonance imaging (MRI) revealed a localized lesion in the right dorsal column. After glucocorticoid therapy, her symptoms and MRI findings improved. Although disease developing less than 24 hours after vaccination is considered an unlikely cause of immuno-associated adverse events following vaccination, we discuss the possible mechanisms involved in early-onset central nervous system inflammation after vaccination in view of preexisting immunopathological susceptibility.
Identifiants
pubmed: 37532545
doi: 10.2169/internalmedicine.2339-23
pmc: PMC10641199
doi:
Substances chimiques
BNT162 Vaccine
0
COVID-19 Vaccines
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3053-3056Références
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