Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma.

Humans T-Lymphocytes, Regulatory Folate Receptor 2 Ligands Tumor-Associated Macrophages Adenocarcinoma of Lung / genetics Adenocarcinoma / genetics Lung Neoplasms / genetics Chemokines / genetics Forkhead Transcription Factors / genetics Tumor Microenvironment / genetics

Journal

Cell death & disease
ISSN: 2041-4889
Titre abrégé: Cell Death Dis
Pays: England
ID NLM: 101524092

Informations de publication

Date de publication:
02 08 2023
Historique:
received: 30 12 2022
accepted: 25 07 2023
revised: 17 07 2023
medline: 4 8 2023
pubmed: 3 8 2023
entrez: 2 8 2023
Statut: epublish

Résumé

An immunosuppressive microenvironment enriched with regulatory CD4

Identifiants

DOI: 10.1038/s41419-023-06021-6 PMID: 37532692 PMC: PMC10397223
pubmed: 37532692
doi: 10.1038/s41419-023-06021-6
pii: 10.1038/s41419-023-06021-6
pmc: PMC10397223
doi:

Substances chimiques

Folate Receptor 2 0
Ligands 0
Chemokines 0
Forkhead Transcription Factors 0
FOLR2 protein, human 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

493

Informations de copyright

© 2023. The Author(s).

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Auteurs

Chan Xiang (C)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Min Zhang (M)

Novogene Co., Ltd., Beijing, 100015, China.
ORCID: 0009-0007-4363-8492

Zhanxian Shang (Z)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Shengnan Chen (S)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Jikai Zhao (J)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Bowen Ding (B)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Dong Jiang (D)

Novogene Co., Ltd., Beijing, 100015, China.

Qian Zhu (Q)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Haohua Teng (H)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Lei Zhu (L)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Jinchen Shao (J)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Ruiying Zhao (R)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Min Ye (M)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.

Yang Yu (Y)

Novogene Co., Ltd., Beijing, 100015, China. yuyang@novogene.com.
ORCID: 0000-0002-4145-3642

Yuchen Han (Y)

Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. ychan@cmu.edu.cn.
ORCID: 0000-0002-2548-5492

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T régulateurs › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs des folates à ancre GPI › Récepteur-2 des folates › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › Macrophages associés aux tumeurs › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Tumeurs › Tumeurs par siège › Tumeurs du thorax › Adénocarcinome pulmonaire › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Carcinomes › Adénocarcinome › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Tumeurs de l'appareil respiratoire › Tumeurs du poumon › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Chimiokines › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif hélice ailée › Facteurs de transcription Forkhead › Single-cell profiling reveals the trajectory...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Microenvironnement cellulaire › Microenvironnement tumoral › Single-cell profiling reveals the trajectory...